N-Acetyl-L-cysteine attenuates titanium dioxide nanoparticle (TiO NP)-induced autophagy in male germ cells.

Titanium dioxide nanoparticles (TiO NPs) are widely used in consumer products, raising concerns about their impact on human health. This study investigates the effects of TiO NPs on male germ cells while focusing on cell proliferation inhibition and underlying mechanisms. This was done by utilizing mouse GC-1 spermatogonia cells, an immortalized spermatogonia cell line.

Bisphenol Analogs Downregulate the Self-Renewal Potential of Spermatogonial Stem Cells.

Purpose: In this study, we investigated the effect of bisphenol-A (BPA) and its major analogs, bisphenol-F (BPF), and bisphenol-S (BPS), on spermatogonial stem cells (SSCs) populations using SSC culture and transplantation models.

Materials And Methods: SSCs enriched from 6- to 8-day-old C57BL/6-eGFP⁺ male mice testes were treated with varying concentrations of bisphenols for 7 days to examine bisphenol-derived cytotoxicity and changes in SSC characteristics. We utilized flow cytometry, immunocytochemistry, real-time quantitative reverse transcription-PCR, and western blot analysis.

Short communication: In ovo injection of all-trans retinoic acid causes adipocyte hypertrophy in embryos but lost its effect in posthatch chickens.

The regulation of adipose deposition in broiler chickens is an important factor for production efficiency to poultry producers and health concerns to customers. Although vitamin A and its metabolite [all-trans retinoic acid (atRA)] have been used for studies on adipogenesis in mammals and avian, effects of embryonic atRA on adipose development in embryonic (E) and posthatch (D) ages in broiler chickens have not been studied yet. Different concentrations of atRA (0 M-2 μM) were injected in broiler eggs at E10, and adipose tissues were sampled at E16.

Effects of Video-Based Information Provision Using a Smart Pad on Patients Undergoing Bone Marrow Biopsy.

The purpose is to determine the effect of video-based information provision using a smart pad on uncertainty, anxiety, physiological parameters, pain, and educational satisfaction among patients hospitalized for a bone marrow biopsy. This study was done with a pre-/posttest nonequivalent control group design. The subjects were 65 patients in the hematology-oncology ward of a university hospital in Cheongju, South Korea, who underwent a bone marrow biopsy between August 2017 and May 2018.