Numerical Simulation of Flow Field and Ion Transport for Different Ion Source Sampling Interfaces of a Mass Spectrometer.

Understanding ion transport mechanisms in the flow expansion section of the first vacuum region of a mass spectrometer (MS) with an atmospheric pressure ionization source is essential for optimizing the MS sampling interface design. In this study, numerical simulations of three types of ions in two different MS interface designs have been carried out. In contrast to previously reported numerical studies, nonequilibrium gas dynamics due to rarefied gas effects has been considered in modeling the flow expansion and a realistic space charge effect has been considered in a continuous ion injection mode.

Numerical Simulation of Ion Transport in a Nano-Electrospray Ion Source at Atmospheric Pressure.

Understanding ion transport properties from the ion source to the mass spectrometer (MS) is essential for optimizing device performance. Numerical simulation helps in understanding of ion transport properties and, furthermore, facilitates instrument design. In contrast to previously reported numerical studies, ion transport simulations in a continuous injection mode whilst considering realistic space-charge effects have been carried out.

Nonequilibrium gaseous heat transfer in pressure-driven plane Poiseuille flow.

Nonequilibrium heat and mass transfer in a pressure-driven plane Poiseuille flow is investigated using the direct simulation Monte Carlo method from the early slip to the free molecular regime. Our investigations reveal several nonintuitive, nonequilibrium thermal flow patterns, including expansion cooling near the walls, a nonconstant pressure profile, and counter-gradient heat transfer along the channel center-line. A bimodal trend in the tangential heat flux is found in the slip and the early transition regime.