HEMATOLOGICAL AND BIOCHEMICAL PARAMETERS AS PROGNOSTIC INDICATORS FOR SUCCESSFUL REHABILITATION IN CONFISCATED TEMMINCK'S PANGOLINS ().

The establishment of prognostic indicators in wildlife patients aids clinical decision-making and resource allocation. Hematological and plasma biochemical parameters were evaluated as potential prognostic indicators in wild Temminck's pangolins () rescued from the illegal wildlife trade. In this prospective cohort study, EDTA and lithium heparin blood samples were collected from the ventral coccygeal vein in 41 pangolins within 48 h of confiscation and before veterinary intervention.

Inequalities in the prevalence recording of 205 chronic conditions recorded in primary and secondary care for 12 million patients in the English National Health Service.

Background: Understanding the prevalence of diseases and where it is detected and recorded in healthcare settings is important for planning effective prevention and care provision. We examined inequalities in the prevalence of 205 chronic conditions and in the care setting where the related diagnoses were recorded in the English National Health Service.

Methods: We used data from the Clinical Practice Research Datalink Aurum linked with Hospital Episode Statistics for 12.

Research data use in a digital society: a deliberative public engagement.

Background: Sources of public and private data and ways to link them continue to evolve. This offers new opportunities for research, and new reasons for data-holding organisations to form partnerships. While research using these data can be beneficial, there is also a potential for negative consequences for some individuals or groups, including unintended or unanticipated effects.

UNLEASH: Ultralow Nanocluster Loading of Pt via Electro-Acoustic Seasoning of Heterocatalysts.

The shift toward sustainable energy has fueled the development of advanced electrocatalysts to enable green fuel production and chemical synthesis. To date, no material outperforms Pt-group catalysts for key electrocatalytic reactions, necessitating advanced catalysts that minimize use of these rare and expensive constituents (i.e.

Revealing the diverse electrochemistry of nanoparticles with scanning electrochemical cell microscopy.

The next generation of electroactive materials will depend on advanced nanomaterials, such as nanoparticles (NPs), for improved function and reduced cost. As such, the development of structure-function relationships for these NPs has become a prime focus for researchers from many fields, including materials science, catalysis, energy storage, photovoltaics, environmental/biomedical sensing, The technique of scanning electrochemical cell microscopy (SECCM) has naturally positioned itself as a premier experimental methodology for the investigation of electroactive NPs, due to its unique capability to encapsulate individual, spatially distinct entities, and to apply a potential to (and measure the resulting current of) single-NPs. Over the course of conducting these single-NP investigations, a number of unexpected ( rarely-reported) results have been collected, including fluctuating current responses, and carrying of the NP by the SECCM probe, hypothesised to be due to insufficient NP-surface interaction.

Gastric adenocarcinoma with carcinomatosis and degenerative joint disease of the xiphisternum in a Bactrian camel (Camelus bactrianus).

Gastric adenocarcinomas have been sporadically reported in camelids. This report describes a primary gastric adenocarcinoma and subsequent peritoneal carcinomatosis in a 20-year-old female Bactrian camel (Camelus bactrianus). Numerous metastases were present throughout the omentum, liver, abdominal lymph nodes, intestinal serosa, kidneys and lungs.

High Throughput Correlative Electrochemistry-Microscopy Analysis on a Zn-Al Alloy.

Conventional electrodes and electrocatalysts possess complex compositional and structural motifs that impact their overall electrochemical activity. These motifs range from defects and crystal orientation on the electrode surface to layers and composites with other electrode components, such as binders. Therefore, it is vital to identify how these individual motifs alter the electrochemical activity of the electrode.

Optimizing Amorphous Molybdenum Sulfide Thin Film Electrocatalysts: Trade-Off between Specific Activity and Microscopic Porosity.

Amorphous molybdenum sulfide (a-MoS) is a promising candidate to replace noble metals as electrocatalysts for the hydrogen evolution reaction (HER) in electrochemical water splitting. So far, understanding of the activity of a-MoS in relation to its physical (e.g.

Five years of scanning electrochemical cell microscopy (SECCM): new insights and innovations.

Scanning electrochemical cell microscopy (SECCM) is a nanopipette-based technique which enables measurement of localised electrochemistry. SECCM has found use in a wide range of electrochemical applications, and due to the wider uptake of this technique in recent years, new applications and techniques have been developed. This minireview has collected all SECCM research articles published in the last 5 years, to demonstrate and celebrate the recent advances, and to make it easier for SECCM researchers to remain well-informed.

Drop-cast gold nanoparticles are not always electrocatalytically active for the borohydride oxidation reaction.

The next-generation of energy devices rely on advanced catalytic materials, especially electrocatalytic nanoparticles (NPs), to achieve the performance and cost required to reshape the energy landscape towards a more sustainable and cleaner future. It has become imperative to maximize the performance of the catalyst, both through improvement of the intrinsic activity of the NP, and by ensuring all particles are performing at the level of their capability. This requires not just a structure-function understanding of the catalytic material, but also an understanding of how the catalyst performance is impacted by its environment (substrate, ligand, ).

Intra- and interobserver agreement in computed tomography localization of primary nonhematopoietic hepatic masses and comparison with surgical and histopathological outcomes in 21 cats.

Computed tomography (CT) is commonly used in the staging of hepatic masses and for liver lobectomy planning. Mass location is an important factor in determining the feasibility of resection, including surgical technique and the likelihood of surgical complications. The objectives of this retrospective descriptive cross-sectional, observer agreement, method comparison study were to assess the reliability of CT in correctly determining the hepatic division and lobar site of origin of feline primary nonhematopoietic hepatic masses, compared with surgically confirmed locations.

Practical guidelines for the use of scanning electrochemical cell microscopy (SECCM).

Scanning electrochemical cell microscopy (SECCM) has emerged as a transformative technology for electrochemical materials characterisation and the study of single entities, garnering global adoption by numerous research groups. While details on the instrumentation and operational principles of SECCM are readily available, the growing need for practical guidelines, troubleshooting strategies, and a systematic overview of applications and trends has become increasingly evident. This tutorial review addresses this gap by offering a comprehensive guide to the practical application of SECCM.

Structure-dependent CO reduction on molybdenite (MoS) electrocatalysts.

Scanning electrochemical cell microscopy (SECCM) is employed to directly identify the structure-dependent electrochemical CO reduction reaction (eCORR) activity of molybdenite (MoS) electrocatalysts in an aqueous imidazolium-based aprotic ionic liquid electrolyte. Nanoscale defects, where the edge plane (EP) is exposed, are directly targeted, revealing heightened overall activity (eCORR + the competing hydrogen evolution reaction, HER) over the relatively inactive basal plane (BP). In addition, certain types of defects (, step edges) only exhibit heightened activity under a CO atmosphere (, compared to N), indirectly confirming higher selectivity at these surface sites.

Layering vaccination with antibiotic therapy results in protection and clearance of in Balb/c mice.

Melioidosis is a disease that is difficult to treat due to the causative organism, being inherently antibiotic resistant and it having the ability to invade, survive, and replicate in an intracellular environment. Combination therapy approaches are routinely being evaluated in animal models with the aim of improving the level of protection and clearance of colonizing bacteria detected. In this study, a subunit vaccine layered with the antibiotic finafloxacin was evaluated against an inhalational infection with in Balb/c mice.

Does the choice of induction agent in rapid sequence intubation in the emergency department influence the incidence of post-induction hypotension?

Objective: To describe the effects of different induction agents on the incidence of post-induction hypotension (PIH) and its associated interventions during rapid sequence intubation (RSI) in the ED.

Methods: A single centre retrospective study of patients intubated between 2018 and 2021 was conducted in a regional Australian ED. The impact of induction agent choice, in addition to demographic and clinical factors on the incidence of PIH were determined using descriptive statistics and a multivariate analysis presented as adjusted odds ratios (aORs) and their 95% confidence intervals (CIs).

Multiscale Analysis of Electrocatalytic Particle Activities: Linking Nanoscale Measurements and Ensemble Behavior.

Nanostructured electrocatalysts exhibit variations in electrochemical properties across different length scales, and the intrinsic catalytic characteristics measured at the nanoscale often differ from those at the macro-level due to complexity in electrode structure and/or composition. This aspect of electrocatalysis is addressed herein, where the oxygen evolution reaction (OER) activity of β-Co(OH) platelet particles of well-defined structure is investigated in alkaline media using multiscale scanning electrochemical cell microscopy (SECCM). Microscale SECCM probes of ∼50 μm diameter provide voltammograms from (ca.

An Innovative Design for the Vaginal Speculum.

Introduction: The main objective of this study is to evaluate the effectiveness of a newly designed vaginal speculum, the , in-vitro. The setting of this study was at Florida International University and involved four senior students in the Department of Biomedical Engineering.

Methods: A phantom vaginal model was used to test three variables of the (Visibility, Pressure and Gynecologic Tools tests).

Nasal mucosal IgA levels against SARS-CoV-2 and seasonal coronaviruses are low in children but boosted by reinfection.

Repeated coronavirus infections in childhood drive progressive maturation of systemic immune responses into adulthood. Analyses of immune responses in children have focused primarily upon systemic assessment but the importance of mucosal immunity is increasingly recognised. We studied virus-specific antibody responses in contemporaneous nasal swabs and blood samples from 99 children (4-15 years) and 28 adults (22-56 years), all of whom had prior SARS-CoV-2 infection.

Activity of Finafloxacin against Panels of Respiratory Pathogens.

This study determined the activity of finafloxacin against panels of bacterial strains, representative of those associated with infection in cystic fibrosis patients and predominately isolated from clinical cases of respiratory disease. Many of these isolates were resistant to various antimicrobials evaluated including the aminoglycosides, cephalosporins, carbapenems and fluoroquinolones. Broth microdilution assays were performed at neutral and acidic pH, to determine antimicrobial activity.

Adding epitope compatibility to deceased donor kidney allocation criteria: recommendations from a pan-Canadian online public deliberation.

Background: The widening supply-demand imbalance for kidneys necessitates finding ways to reduce rejection and improve transplant outcomes. Human leukocyte antigen (HLA) epitope compatibility between donor and recipient may minimize premature graft loss and prolong survival, but incorporating this strategy to deceased donor allocation criteria prioritizes transplant outcomes over wait times. An online public deliberation was held to identify acceptable trade-offs when implementing epitope compatibility to guide Canadian policymakers and health professionals in deciding how best to allocate kidneys fairly.