Evaluation of dynamic cerebrovascular autoregulation during liver transplantation.

Background: Cerebrovascular autoregulation in patients with acute and chronic liver failure is often impaired, yet an intact autoregulation is essential for the demand-driven supply of oxygenated blood to the brain. It is unclear, whether there is a connection between cerebrovascular autoregulation during liver transplantation (LTX) and the underlying disease, and if perioperative anesthesiologic consequences can result from this.

Methods: In this prospective observational pilot study, data of twenty patients (35% female) undergoing LTX were analyzed.