The association between weight loss and long term development in quality-of-life among children living with obesity: a pragmatic descriptive intervention study.

Background: Childhood obesity is associated with impaired Quality-of-Life (QoL), increased stigmatization and higher risk of development of depression compared to their peers. This report describes the long-term development in QoL for cohort of children with obesity after a sustainable weight reduction.

Methods: This pragmatic descriptive intervention study enrolled 120 children with obesity, age 5-17 years, in a multifactorial lifestyle intervention.

Uric Acid Is Elevated in Children With Obesity and Decreases After Weight Loss.

Childhood obesity is an increasing condition associated with continuous obesity into adulthood and development of comorbidities. Adult studies show an association between serum uric acid (SUA) levels and body mass index (BMI). The aim of this retro perspective exploratory study was to investigate SUA in obese children and adolescents and the effects of a subsequent weight reduction.

Sustainable weight loss over three years in children with obesity: a pragmatic family-centered lifestyle intervention.

Introduction: Childhood obesity has psychological consequences and increases the risk of continuous obesity into adulthood, associated with development of non-communicable disease (e.g. type 2 diabetes).

[Perianal abscesses in twins].

Perianal abscesses (PA) are relatively common in children, especially in infants. The aetiology of PA is still unknown but several factors point toward a congenital aetiology: 1) it is almost exclusively seen in infants, 2) with a male predominance, 3) predilection sites at 3 and 9 o'clock, 4) the finding of abnormal Morgagni crypts and 5) aberrant epithelial lining. Traditionally, incision and drainage has been the treatment of choice, but several studies suggest conservative management.

[Primary autoimmune neutropenia in children].

Primary autoimmune neutropenia (AIN) is characterised by severe neutropenia and the presence of granulocyte reactive autoantibodies. The pathogenesis of the disease remains unknown and the disease is believed to be underdiagnosed. AIN occurs predominantly at the age of 6-24 months and despite severe neutropenia the symptomatology covers mainly benign infections.

[Neonatal alloimmune neutropenia is a frequently overlooked diagnosis in neonates].

Neonatal alloimmune neutropenia (NIN) results from the destruction of foetal neutrophils by maternal immunoglobulin G-class neutrophil-reactive antibodies crossing the foeto-placental barrier. We report two cases of neonatal patients presenting with unspecific symptoms and persisting neutropenia accompanied by thrombocytosis. Both were subsequently diagnosed with NIN.