Evaluating the treatment utility of the Cognitive Assessment System: A meta-analysis of reading and mathematics outcomes.

There has been a long search for cognitive assessments that reveal aptitudes thought to be useful for treatment planning. In this regard, since the 1990s, there has been some enthusiasm for the Cognitive Assessment System (CAS) and its potential promise for informing treatment due to its alignment of theory, assessment instrument, and suite of interventions. The purpose of this meta-analytic review was to synthesize research pertinent to the treatment utility of the CAS according to a taxonomy of treatment utility.

A wireless W-band 3D-printed temperature sensor based on a three-dimensional photonic crystal operating beyond 1000 C.

In addressing sensing in harsh and dynamic environments, there are no available millimeter-wave chipless and wireless sensors capable of continuous operation at extremely high temperatures. Here we present a fully dielectric wireless temperature sensor capable of operating beyond 1000 C. The sensor uses high-Q cavities embedded within a three-dimensional photonic crystal resonating at 83.

Anti-tumor effects of the eIF4A inhibitor didesmethylrocaglamide and its derivatives in human and canine osteosarcomas.

Inhibition of translation initiation using eIF4A inhibitors like (-)-didesmethylrocaglamide [(-)-DDR] and (-)-rocaglamide [(-)-Roc] is a potential cancer treatment strategy as they simultaneously diminish multiple oncogenic drivers. We showed that human and dog osteosarcoma cells expressed higher levels of eIF4A1/2 compared with mesenchymal stem cells. Genetic depletion of eIF4A1 and/or 2 slowed osteosarcoma cell growth.

Disparities in Psychiatric Emergency Department Boarding of Children and Adolescents.

Importance: Since the COVID-19 pandemic, emergency department boarding of youth with mental health concerns has increased.

Objective: To summarize characteristics (including gender, age, race, ethnicity, insurance, diagnosis, and barriers to placement) of youth who boarded in emergency departments while awaiting inpatient psychiatric care and to test for racial, ethnic, and gender disparities in boarding lengths and inpatient admission rates after boarding. Secondarily, to assess whether statewide demand for inpatient psychiatric care correlated with individual outcomes.

Anti-tumor Effects of the eIF4A Inhibitor Didesmethylrocaglamide and Its Derivatives in Human and Canine Osteosarcomas.

Inhibition of translation initiation using eIF4A inhibitors like (-)-didesmethylrocaglamide [(-)-DDR] and (-)-rocaglamide [(-)-Roc] is a potential cancer treatment strategy as they simultaneously diminish multiple oncogenic drivers. We showed that human and dog osteosarcoma cells expressed high levels of eIF4A1/2, particularly eIF4A2. Genetic depletion of eIF4A1 and/or 2 slowed osteosarcoma cell growth.

Smarter continuity in an era of expanding challenges in primary care.

If we are to achieve the clinical and economic benefits of primary care and care continuity, the implementation and evaluation of strategies that reward clinicians and patients are warranted.

Correction: Occurrence and spatial distribution of heavy metals in landfill leachates and impacted freshwater ecosystem: An environmental and human health threat.

[This corrects the article DOI: 10.1371/journal.pone.

Hands-On Neuroinformatics Education at the Crossroads of Online and In-Person: Lessons Learned from NeuroHackademy.

NeuroHackademy ( https://neurohackademy.org ) is a two-week event designed to train early-career neuroscience researchers in data science methods and their application to neuroimaging. The event seeks to bridge the big data skills gap by introducing participants to data science methods and skills that are often ignored in traditional curricula.

Seven-Year Revision Rates for Cochlear Implants in Pediatric and Adult Populations of an Integrated Healthcare System.

Objective: We assessed three cochlear implant (CI) suppliers: Advanced Bionics, Cochlear Limited, and MED-EL, for implant revision requiring reoperation after CI placement.

Study Design: Retrospective cohort study of integrated-health-system database between 2010 and 2021. Separate models were created for pediatric (age <18) and adult (age ≥18) cohorts.

High-density lipoprotein (HDL) as an indicator for alcohol use in a psychiatrically ill population.

Aims: To examine the cross sectional and longitudinal associations between the Alcohol Use Disorders Identification Test-Concise (AUDIT-C) and differences in high-density lipoprotein (HDL) in a psychiatrically ill population.

Methods: Retrospective observational study using electronic health record data from a large healthcare system, of patients hospitalized for a mental health/substance use disorder (MH/SUD) from 1 July 2016 to 31 May 2023, who had a proximal AUDIT-C and HDL (N = 15 915) and the subset who had a repeat AUDIT-C and HDL 1 year later (N = 2915). Linear regression models examined the association between cross-sectional and longitudinal AUDIT-C scores and HDL, adjusting for demographic and clinical characteristics that affect HDL.

Human V4 size predicts crowding distance.

Visual recognition is limited by both object size (acuity) and spacing. The spacing limit, called "crowding", is the failure to recognize an object in the presence of other objects. Here, we take advantage of individual differences in crowding behavior to investigate its biological basis.

Convolutional neural network-based classification of glaucoma using optic radiation tissue properties.

Background: Sensory changes due to aging or disease can impact brain tissue. This study aims to investigate the link between glaucoma, a leading cause of blindness, and alterations in brain connections.

Methods: We analyzed diffusion MRI measurements of white matter tissue in a large group, consisting of 905 glaucoma patients (aged 49-80) and 5292 healthy individuals (aged 45-80) from the UK Biobank.

Administration and Scoring Errors on the Woodcock-Johnson IV Tests of Achievement: Before and During COVID-19.

Eighty Woodcock-Johnson IV Tests of Achievement protocols from 40 test administrators were examined to determine the types and frequencies of administration and scoring errors made. Non-critical errors (e.g.

Self-Pay Outpatient Mental Health Care for Children and Adolescents, by Socioeconomic Status.

Objective: Many parents struggle to find mental health care for their children, and many mental health clinicians do not accept insurance payments. The authors aimed to estimate the frequency and cost of self-pay psychotherapy and psychotropic medication management visits for youths and to determine how service use varies by family income.

Methods: A descriptive cross-sectional analysis was performed among youths ages 5-17 years in the 2018-2020 Medical Expenditure Panel Survey.

Vaccine value profile for Klebsiella pneumoniae.

Klebsiella pneumoniae causes community- and healthcare-associated infections in children and adults. Globally in 2019, an estimated 1.27 million (95% Uncertainty Interval [UI]: 0.

Suppression of the Coffee Ring Effect in a Single Solvent-Based Silicon Nanoparticle Ink.

Silicon (Si) is made printable by dispersing Si nanoparticles in a single organic solvent. Viscoelastic properties of the prepared inks as well as the uniformity of inkjet-printed thin films are investigated in dependence on the Si volume fraction. It has been demonstrated that no ink additives are needed to completely suppress the occurrence of the coffee ring effect.

Lead-free organic-inorganic azetidinium alternating metal cation bromide: [(CH)NH]AgBiBr, a perovskite-related absorber.

In the last decade, organic-inorganic hybrid halide perovskite materials have developed into a very large research area in photovoltaics and optoelectronics as promising light harvesters. Lead-free double perovskites have recently been investigated as an environmentally friendly alternative to the lead-containing compositions. However, lead-free organic-inorganic hybrid halide double perovskites have so far rarely been produced due to a certain complexity in their synthesis.

Dataset for PCBs and OCPs in intertidal sediment and surface-mixed layer water from Lagos lagoon, southwest coast of Nigeria.

Sediment quality and the integrity of coastal aquatic ecosystems are deteriorating, particularly in regions with unregulated discharges of chemical pollutants into the environment. Although organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs) have been banned in recent decades for their adverse effects on the environment and human and animal health, these organic micropollutants are frequently detected in many aquatic systems. This dataset reports baseline concentrations of 27 PCBs and 20 OCPs analysed in surface-mixed layer water and sediment samples collected from designated sampling locations in the Lagos lagoon, off the Gulf of Guinea, Nigeria.

Value-Based Insurance Design: Clinically Nuanced Consumer Cost-Sharing for Mental Health Services.

Background: While consumer cost-sharing is a widely used strategy to mitigate health care spending, numerous studies have demonstrated that even modest levels of out-of-pocket cost are associated with lower use of medical care, including clinically necessary, high-value services. Within mental health care, increases in cost-sharing are associated with reductions in use of mental health care and psychotropic medication use. Further, these reductions in mental health services and treatments can lead to downstream consequences including worsening of psychiatric illness and increased need for acute care and psychiatric hospitalization.

Remodeling Broken Systems: Addressing the National Emergency in Child and Adolescent Mental Health.

A national emergency in child and adolescent mental health was declared in the United States in 2021 in the wake of the COVID-19 pandemic. This Open Forum discusses potential solutions to better support child and adolescent mental health by improving or expanding school-based mental health services, child psychiatry access programs, virtual mental health services, and new models of care (e.g.

Medical and Psychiatric Care Preceding the First Psychotic Disorder Diagnosis.

Background: Individuals with psychotic symptoms experience substantial morbidity and have shortened life expectancies; early treatment may mitigate the worst effects. Understanding care preceding a first psychotic disorder diagnosis is critical to inform early detection and intervention.

Study Design: In this observational cohort study using comprehensive information from the Massachusetts All-Payer Claims Database, we identified the first psychotic disorder diagnosis in 2016, excluding those with historical psychotic disorder diagnoses in the prior 48 months among those continuous enrollment data.

Reliability of stored river water as an alternative for consumption in Ekpoma, Nigeria: a human health risk assessment.

With looming global water-related issues, the monitoring of water quality for household and industrial consumption has become more pertinent. Rivers in nearby towns serve as primary water sources for Ekpoma town. 123 samples of stored river water were collected from 41 sampling locations and physical properties - pH, electrical conductivity (EC), salinity, temperature, and total dissolved solids (TDS) - were measured in situ using the Hanna edge® Multiparameter EC/TDS/Salinity Meter-HI2030.

Tacking upwind: reducing spending among high-risk commercially insured patients.

Objectives: The study examined a commercial accountable care organization (ACO) population and then assessed the impact of an integrated care management program on medical spending and clinical event rates.

Study Design: Retrospective cohort study of high-risk individuals (n = 487) in a population of 365,413 individuals aged 18 to 64 years within the Mass General Brigham health system who were part of commercial ACO contracts with 3 large insurers between 2015 and 2019.

Methods: Using medical spending claims and other enrollment data, the study assessed the demographic and clinical characteristics, medical spending, and clinical event rates of patients in the ACO and its high-risk care management program.