Tyrosinemia type II: a challenge for ophthalmologists and dermatologists.

Tyrosinemia type II was suspected in a 13-month-old child with recurrent photophobia, tearing, and hyperkeratotic lesions on the palms and soles. Laboratory tests revealed high tyrosine levels in blood and urine. All the symptoms promptly improved after the institution of a low tyrosine diet.

Sneddon's syndrome and primary antiphospholipid syndrome: a case report.

The association between livedo reticularis and cerebrovascular accidents is known as Sneddon's syndrome. We describe a case in which Sneddon's syndrome appeared as a clinical manifestation of primary antiphospholipid syndrome.

Prevention of post-herpetic neuralgia. Evaluation of treatment with oral prednisone, oral acyclovir, and radiotherapy.

The effects of prednisone, oral acyclovir, and radiotherapy were compared with placebo in the prevention of post-herpetic neuralgia. No treatment used was able to prevent, with statistical significance, post-herpetic neuralgia, although prednisone and acyclovir showed some pain reduction in the acute phase. Radiotherapy was of no value in either the acute or post-herpetic phase.

Botryomyces caespitosus as an agent of cutaneous phaeohyphomycosis.

The second known case of a skin infection caused by Botryomyces caespitosus is reported. This case has made it possible to describe the characteristics of this fungus in vivo and to establish it as another agent of phaeohyphomycosis.

[Linear IgA dermatitis. Presentation of a clinical case].

A case of linear IgA disease is presented. In association with typical cutaneous lesions and linear IgA deposits along the basal membrane, the Authors describe the severe ocular involvement with blindness of the right eye. The Authors also underline palmar involvement with hyperkeratosis and scleroderma-like aspect.

Isolation of Chlamydia trachomatis from the prostatic cells in patients affected by nonacute abacterial prostatitis.

To assess the presence of Chlamydia trachomatis in nonacute abacterial prostatitis 30 patients with urethral cultures positive for Chlamydia trachomatis underwent microbiological studies, including cultures of transrectal aspiration biopsies of the prostate. Chlamydia trachomatis was isolated from 10 of the prostatic specimens (33 per cent). In 3 cases a nonspecific cytopathogenic effect caused the destruction of the tissue cultures.

Paracoccidioidomycosis (South American blastomycosis): a report of an imported case previously diagnosed as tuberculosis.

A case of paracoccidioidomycosis, previously treated for tuberculosis for two years, is reported. Combined treatment with oral ketoconazole and sulfamethoxypyridazine was successful. The problem of a low index of suspicion among physicians for tropical mycoses, which are very rarely observed in Italy, is discussed.

Multiple persistent keratoacanthomas: treatment with oral etretinate.

Multiple keratoacanthomas (KAs) of the Ferguson-Smith type represent a rare and distinctive disease for which treatment is difficult and often unrewarding. Two patients with multiple KAs of this variety, who were successfully treated with oral etretinate, are described. Our cases support the conclusion that oral retinoids have to be added to the treatment modalities for this entity.

[Sacral herpes zoster: a cause of urination and defecation disorders].

A case of sacral herpes zoster associated with alteration of urination and defecation is presented. The pathogenetic mechanisms of these unusual complications are discussed.

Reiter's disease: successful treatment of the skin manifestations with oral etretinate.

Cutaneous manifestations in a case of Reiter's disease were successfully treated by oral etretinate administration. The clinical and histopathological similarities between the skin lesions of Reiter's disease and those of pustular psoriasis, which is known to respond to aromatic retinoids, suggested this treatment.

Erosive lichen planus involving the glans penis alone.

A 71-year-old white man was first seen in September 1978. He complained of an asymptomatic recurrent red patch, which had been slowly enlarging for two months on the glans penis. The patient stated he had a similar lesion a year before, which disappeared completely after one month of treatment with a topical corticosteroid.

White sponge nevus: successful treatment with penicillin.

White sponge nevus is a rare, benign, inherited disorder of the mucous membranes, affecting mainly the oral mucosa. A case is reported of white sponge nevus, which showed a definite improvement following penicillin administration.