Duloxetine for mild to moderate postprostatectomy incontinence: preliminary results of a randomised, placebo-controlled trial.

Background: Duloxetine is effective in the management of stress urinary incontinence (SUI) in women but has been poorly evaluated in the treatment of SUI following radical prostatectomy (RP).

Objective: To establish the superiority of duloxetine over placebo in SUI after RP.

Design, Setting, And Participants: We conducted a prospective, randomised, placebo-controlled, double-blind, monocentric superiority trial.

[Biomedical research legislation applicable since 28 August 2006].

The new legislation concerning biomedical research entered into force on 28 August 2006. This legislation, which goes further than the recommendations of European Directive 2001/20/EC, introduces several modifications reinforcing the role of the Comité de Protection des Personnes (Ethics Committee) and the various administrations. The protection of subjects is reinforced by increased control of participants and investigators.

[Macroscopic haematuria after transurethral resection of the prostate].

Unlabelled: Although macroscopic haematuria during the month following transurethral resection of the prostate, due to sloughing of necrotic tissue, is a phenomenon well known to urologists since introduction of endoscopic resection, its pathophysiological and epidemiological characteristics are poorly defined. The objective of this retrospective study was to define the incidence of serious macroscopic haematuria after transurethral resection of the prostate (TURP) and to identify the risk factors for macroscopic haematuria.

Patients And Methods: The hospital database was used to identify patients treated by TURP between 1997 and 2004 and rehospitalized during the 31 days following the procedure.