Publications by authors named "Benoit Beliard"
Acute spinal cord injury (SCI) leads to severe damage to the microvascular network. The process of spontaneous repair is accompanied by formation of new blood vessels; their functionality, however, presumably very important for functional recovery, has never been clearly established, as most studies so far used fixed tissues. Here, combining ultrafast Doppler imaging and ultrasound localization microscopy (ULM) on the same animals, we proceeded at a detailed analysis of structural and functional vascular alterations associated with the establishment of chronic SCI, both at macroscopic and microscopic scales.
View Article and Find Full Text PDFArticle Synopsis
- The study tackled the difficult task of imaging the trigeminal ganglion (TG), a small and deep-seated structure, by combining advanced imaging techniques to analyze blood flow and respond to orofacial stimuli in rats.
- Functional ultrasound imaging successfully captured strong hemodynamic responses in the TG, linked to various mechanical and chemical stimulations of nociceptive fibers in the face, highlighting the area’s sensitivity despite the limited number of sensory neurons.
- This innovative imaging method not only visualized the vasculature of the TG but also offers new insights for understanding the mechanisms of trigeminal pain, paving the way for future research in treatment options.