Publications by authors named "Benneker L"

Article Synopsis
  • The study evaluated the reliability of the AO Spine-DGOU Osteoporotic Fracture classification system using a cross-sectional survey with 23 trauma experts rating 33 cases at two different times.
  • The calculated kappa statistics indicated moderate inter-rater agreement and substantial intra-rater reproducibility, suggesting that while raters differed slightly, individual consistency was high.
  • The findings highlight the importance of training in improving the reliability of the classification system for identifying fracture patterns and guiding treatment.
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Study Design: Broad narrative review.

Objectives: To review and summarize the evolution of spinopelvic fixation (SPF) and its implications on clinical care.

Methods: A thorough review of peer-reviewed literature was performed on the historical evolution of sacropelvic fixation techniques and their respective advantages and disadvantages.

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Study Design: Biomechanical Cadaveric Study.

Objectives: Following the successful use of a novel implantable sensor (Monitor) in evaluating the progression of fracture healing in long bones and posterolateral fusion of the spine based on implant load monitoring, the aim of this study was to investigate its potential to assess healing of transosseous fractures of a lumbar vertebra stabilized with a pedicle-screw-rod construct.

Methods: Six human cadaveric spines were instrumented with pedicle screws and rods spanning L3 vertebra.

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Study Design: Literature review with clinical recommendations.

Objective: To highlight important studies about osteoporotic spinal fractures (OF) that may be integrated into clinical practice based on the assessment of the AO Spine KF Trauma and Infection group key opinion leaders.

Methods: 4 important studies about OF that may affect current clinical practice of spinal surgeons were selected and reviewed with the aim of providing clinical recommendations to streamline the journey of research into clinical practice.

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Article Synopsis
  • The study compared outcomes of two surgical fixation methods—transiliac-transsacral screw fixation (TIS) and lumbopelvic fixation (LPS)—for treating certain sacral fractures in patients with minimal displacement.
  • Both groups showed no significant differences in low back pain and mobility post-surgery at multiple check-in points, indicating similar recovery experiences.
  • However, the TIS group had shorter surgery times, less blood loss, fewer reoperations, and a shorter hospital stay compared to the LPS group, suggesting TIS may be a more efficient option.
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Objectives: To evaluate the clinical 10 year outcome of patients treated with percutaneous vertebroplasty for vertebral compression fractures and to determine the incidence of new fractures in this time interval, as well as the mortality of the patients who underwent this procedure.

Methods: All patients undergoing vertebroplasty for vertebral compression fractures between May 2007 until July 2008 were prospectively followed up at 10 years postoperatively. Patients were assessed for radiologic outcome and self-reported outcome parameters (PROs).

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Introduction: Deformity of the spinal column after trauma could lead to pain, impaired function, and may sometimes necessitate extensive and high-risk surgery. This 'condition' has multiple terms and definitions that are used in research and clinics. A specific term and definition of this condition however is still lacking.

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Purpose: To evaluate feasibility, internal consistency, inter-rater reliability, and prospective validity of AO Spine CROST (Clinician Reported Outcome Spine Trauma) in the clinical setting.

Methods: Patients were included from four trauma centers. Two surgeons with substantial amount of experience in spine trauma care were included from each center.

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Study Design: A prospective study.

Objective: to evaluate the impact of vertebral body comminution and Posterior Ligamentous Complex (PLC) integrity on the treatment recommendations of thoracolumbar fractures among an expert panel of 22 spine surgeons.

Methods: A review of 183 prospectively collected thoracolumbar burst fracture computed tomography (CT) scans by an expert panel of 22 trauma spine surgeons to assess vertebral body comminution and PLC integrity.

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Study Design: Retrospective analysis of prospectively collected data.

Objectives: To compare decision-making between an expert panel and real-world spine surgeons in thoracolumbar burst fractures (TLBFs) without neurological deficits and analyze which factors influence surgical decision-making.

Methods: This study is a sub-analysis of a prospective observational study in TL fractures.

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Study Design: Reliability study utilizing 183 injury CT scans by 22 spine trauma experts with assessment of radiographic features, classification of injuries and treatment recommendations.

Objectives: To assess the reliability of the AOSpine TL Injury Classification System (TLICS) including the categories within the classification and the M1 modifier.

Methods: Kappa and Intraclass correlation coefficients were produced.

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Article Synopsis
  • This study analyzed data from 183 cases of thoracolumbar burst fractures to understand factors affecting treatment agreement among experts.
  • Only 4.4% of cases reached full expert consensus, with 44.3% in the agreement group and 55.7% in the equipoise group, indicating significant uncertainty among the panel.
  • The agreement group showed greater certainty regarding PLC disruption and more usage of the M1 modifier, while the equipoise group had a higher proportion of more severe A3/A4 fractures, suggesting a need for further research on how comminution influences treatment decisions.
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Study Design: This paper presents a description of a conceptual framework and methodology that is applicable to the manuscripts that comprise this focus issue.

Objectives: Our goal is to present a conceptual framework which is relied upon to better understand the processes through which surgeons make therapeutic decisions around how to treat thoracolumbar burst fractures (TL) fractures.

Methods: We will describe the methodology used in the AO Spine TL A3/4 Study prospective observational study and how the radiographs collected for this study were utilized to study the relationships between various variables that factor into surgeon decision making.

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Study Design: Predictive algorithm via decision tree.

Objectives: Artificial intelligence (AI) remain an emerging field and have not previously been used to guide therapeutic decision making in thoracolumbar burst fractures. Building such models may reduce the variability in treatment recommendations.

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Study Design: Retrospective analysis of prospectively collected data.

Objective: To evaluate how preexisting adjacent segment degeneration status impacts revision risk for adjacent segment disease (ASD) after lumbar fusions.

Summary Of Background Data: ASD incurs late reoperations after lumbar fusion surgeries.

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Reliable and timely assessment of bone union between vertebrae is considered a key challenge after spinal fusion surgery. Recently, a novel sensor concept demonstrated the ability to objectively assess posterolateral fusion based on continuous implant load monitoring. The aim of this study was to investigate systematically the concept in a mono-segmental fusion model using an updated sensor setup.

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Purpose: Assessing the diagnostic performance and supplementary value of whole-body computed tomography scout view (SV) images in the detection of thoracolumbar spine injuries in early resuscitation phase and identifying frequent image quality confounders.

Methods: In this retrospective database analysis at a tertiary emergency center, three blinded senior experts independently assessed SV to detect thoracolumbar spine injuries. The findings were categorized according to the AO Spine classification system.

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Study Design: Global cross-sectional survey.

Objective: To establish a surgical algorithm for sacral fractures based on the Arbeitsgemeinschaft für Osteosynthesefragen (AO) Spine Sacral Injury Classification System.

Summary Of Background Data: Although the AO Spine Sacral Injury Classification has been validated across an international audience of surgeons, a consensus on a surgical algorithm for sacral fractures using the Sacral AO Spine Injury Score (Sacral AOSIS) has yet to be developed.

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Study Design: Bibliometric analysis.

Objectives: An analysis of the literature related to the assessment and management of spinal trauma was undertaken to allow the identification of top contributors, collaborations and research trends.

Methods: A search to identify original articles published in English between 2011 and 2020 was done using specific keywords in the Web of Science database.

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Study Design: Survey of cases.

Objective: To evaluate the opinion of experts in the diagnostic process of clinically relevant Spinal Post-traumatic Deformity (SPTD).

Summary Of Background Data: SPTD is a potential complication of spine trauma that can cause decreased function and quality of life impairment.

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Purpose: Lumbar spinal fusion surgery (LSFS) is common for lumbar degenerative disorders. The objective was to develop clinical prediction rules to identify which patients are likely to have a favourable outcome to inform decisions regarding surgery and rehabilitation.

Methods: A prospective observational study recruited 600 (derivation) and 600 (internal validation) consecutive adult patients undergoing LSFS for degenerative lumbar disorder through the British Spine Registry.

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Background: Traumatic cervical spine (c-spine) injuries account for 10% of all spinal injuries. The c-spine is prone to injury by blunt acceleration/deceleration traumas. The Canadian C-Spine rule and NEXUS criteria guide clinical decision-making but lack consensus on imaging modality when necessary.

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Article Synopsis
  • The study examines how pro-inflammatory cytokines affect human annulus fibrosus cells (hAFCs) and their ability to sensitize dorsal root ganglion (DRG) cells.
  • Celecoxib (cxb) was tested to see if it could inhibit this sensitization, with results showing that it effectively reduced PGE-2 production in hAFCs and lowered DRG cell sensitivity to bradykinin.
  • Overall, the findings suggest that cxb may be beneficial in minimizing nerve sensitization related to inflamed hAFCs.
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Purpose: The AO Spine PROST (Patient Reported Outcome Spine Trauma) was developed for people with spine trauma and minor or no neurological impairment. The purpose is to investigate health professionals' perspective on the applicability of the AO Spine PROST for people with motor-complete traumatic or non-traumatic spinal cord injury (SCI), using a discussion meeting and international survey study.

Methods: A discussion meeting with SCI rehabilitation physicians in the Netherlands was performed, followed by a worldwide online survey among the AO Spine International community, involved in the care of people with SCI.

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