Publications by authors named "Benli Zhou"
Background: The performance of live attenuated Japanese Encephalitis SA 14-14-2 vaccine (CD-JEV) among children previously given inactivated mouse brain-derived JE vaccine (IMBV) is unknown. We evaluated the safety and immunogenicity of CD-JEV administered to 2- and 5-year-old children in Sri Lanka.
Methods: In this open-label, single arm trial in the Colombo District of Sri Lanka, generally healthy children 2 and 5years of age who had previously received two and three doses of IMBV, respectively, were administered one dose of CD-JEV subcutaneously.
Introduction: To facilitate introduction of live attenuated SA 14-14-2 Japanese encephalitis vaccine (LJEV) into the National Immunization Programme of Sri Lanka, we evaluated the safety and immunogenicity of co-administration of LJEV and measles vaccine at 9 months of age. Serum immune responses were evaluated post-vaccination on days 28, 180, and 365 using JE neutralization test and anti-measles IgG ELISA.
Results: 278 infants received one dose of LJEV and measles vaccine.
Japanese encephalitis (JE) virus is a major cause of disease, disability, and death in Asia. An effective, live, attenuated JE vaccine (LJEV) is available; however, its use in routine immunization schedules is hampered by lack of data on concomitant administration with measles vaccine (MV). This study evaluated the immunogenicity and reactogenicity of LJEV and MV when administered at the same or separate study visits in infants younger than 1 year of age.
View Article and Find Full Text PDF[Study on the disabilities in aged 0-7 years children in Shenzhen, China].
Zhonghua Liu Xing Bing Xue Za Zhi
November 2003
Article Synopsis
- The study aimed to assess the prevalence of various disabilities (vision, mental, language, psychiatric, extremity, and hearing) in children aged 0 to 7 years in Shenzhen, involving a sample of 77,727 children.
- Results showed an overall disability prevalence of 5.59 per thousand, with mental and language disabilities being the most common, while vision disabilities were the least common, with a noted increase in prevalence with age.
- The findings indicated that while the overall prevalence of disabilities in Shenzhen is lower compared to national rates from 1989, it is still significantly higher than similar studies conducted in Japan, warranting further investigation into possible causes.