N-butylphthalide (NBP) ameliorated ischemia/reperfusion-induced skeletal muscle injury in male mice via activating Sirt1/Nrf2 signaling pathway.

N-butylphthalide (NBP) has been reported to have potential protective effects in ischemic stroke via its antioxidative properties. The present study was aimed to investigate the protective effects of NBP on ischemia/reperfusion (I/R)-induced skeletal muscle injury. Mouse model of I/R-induced skeletal muscle injury and hypoxia/reoxygenation (H/R)-induced C2C12 myotube injury model were constructed to test the protective effects of NBP both in vivo and in vitro.

Bipolar catheter ablation strategies for outflow tract ventricular arrhythmias refractory to unipolar ablation.

Introduction: Conventional unipolar catheter ablation (UA) is generally effective for the treatment of outflow tract ventricular arrhythmias (OT-VAs). However, deep foci refractory to UA remains a clinical challenge. The present study evaluated the efficacy and safety of bipolar ablation (BA) in the treatment of OT-VAs refractory to UA.

Kinetics of chromium (VI) reduction and phenol biodegradation by Pseudomonas sp. JF122.

Kinetics of chromium (VI) reduction and phenol biodegradation by a pure culture of Pseudomonas sp. JF122 was studied. High inoculum (volume) increased both chromium (VI) reduction and phenol biodegradation velocity, which are ascribable to shorter acclimation period requirement for cell growth.