Objective: The purpose of this study was to describe the impact of enteral glyburide on cerebral edema formation and hypoglycemia when used to treat patients diagnosed with acute ischemic stroke (AIS).
Methods: This study was a single-center, retrospective medical record review that included all patients aged ≥18 years diagnosed with AIS who received ≥1 dose of enteral glyburide for the prevention of cerebral edema from January 1, 2018 to March 31, 2022. The primary outcome was the percentage of patients requiring intervention for cerebral edema management after glyburide initiation, and the safety outcome was the occurrence of hypoglycemia in this patient population.
A 23-year-old man presented with a 1-month history of a red and painful right eye, with visual acuity reduced to hand motions. Examination showed uveitis with keratic precipitates, cells and flare in the anterior chamber, and vitritis that obscured visualization of the right fundus. The following week, he was noted to have the following left-sided findings: reduced visual acuity (6/18), painless upper eyelid edema, an elevated, pink bulbar conjunctival lesion, limitation of ocular abduction, paresthesia in the V1 and reduced sensation in the V2 distributions.
View Article and Find Full Text PDFAsia Pac J Ophthalmol (Phila)
May 2022
Purpose: Artificial intelligence (AI) technology is poised to revolutionize modern delivery of health care services. We set to evaluate the patient perspective of AI use in diabetic retinal screening.
Design: Survey.
Data collected from a moving lidar sensor can produce an accurate digital representation of the physical environment that is scanned, provided the time-dependent positions and orientations of the lidar sensor can be determined. The most widely used approach to determining these positions and orientations is to collect data with a GNSS/INS sensor. The use of dual-antenna GNSS/INS sensors within commercial UAS-lidar systems is uncommon due to the higher cost and more complex installation of the GNSS antennas.
View Article and Find Full Text PDFModern lidar sensors are continuing to decrease in size, weight, and cost, but the demand for fast, abundant, and high-accuracy lidar observations is only increasing. The Livox Mid-40 lidar sensor was designed for use within sense-and-avoid navigation systems for autonomous vehicles, but has also found adoption within aerial mapping systems. In order to characterize the overall quality of the point clouds from the Mid-40 sensor and enable sensor calibration, a rigorous model of the sensor's raw observations is needed.
View Article and Find Full Text PDFMany lightweight lidar sensors employed for UAS lidar mapping feature a fan-style laser emitter-detector configuration which results in a non-uniform pattern of laser pulse returns. As the role of UAS lidar mapping grows in both research and industry, it is imperative to understand the behavior of the fan-style lidar sensor to ensure proper mission planning. This study introduces sensor modeling software for scanning simulation and analytical equations developed in-house to characterize the non-uniform return density (i.
View Article and Find Full Text PDFUnlabelled: The authors evaluated the impact of genetic screening for familial hypercholesterolaemia (FH) in a lipid clinic cohort of patients with definite and possible FH as defined by the Simon Broome Register (SBR) criteria.
Methods: Patients with a lipid clinic diagnosis of definite and possible FH based on the SBR criteria were referred to a nurse-led regional service for FH genetic testing.
Findings: 140 patients were referred for genetic testing.
We demonstrate a simple multi-wavelength optical source suitable for spectroscopic optical resolution photoacoustic microscopy (OR-PAM) of lipid-rich tissue. 1064 nm laser pulses are converted to multiple wavelengths beyond 1300 nm via nonlinear optical propagation in a birefringent optical fiber. OR-PAM experiments with lipid phantoms clearly show the expected absorption peak near 1210 nm.
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