Utility of Thrombectomy in Nonagenarians: A Scoping Review.

Background: Mechanical thrombectomy represents a mainstay of management for acute ischemic stroke in the setting of large vessel occlusion. However, there are no clinical practice guidelines defining the role of thrombectomy at the extremes of age. In this scoping review, we aimed to summarize the existing medical and neurosurgical literature pertaining to mechanical thrombectomy in nonagenarians.

Contrast-enhanced ultrasound (CEUS) for the characterization of intra-scrotal lesions.

Contrast-enhanced ultrasound (CEUS) has emerged as a promising imaging modality for the characterization of hepatic and renal lesions. However, there is a paucity of data describing the use of CEUS for the evaluation of intra-scrotal pathology. In the following review, we describe the clinical utility of CEUS for the characterization and differentiation of common and uncommon intra-scrotal conditions, including testicular torsion, infection, trauma, and benign and malignant intratesticular and extratesticular neoplasms.

Anti-N-methyl-D-aspartate receptor-associated encephalitis: A review of clinicopathologic hallmarks and multimodal imaging manifestations.

Anti-N-methyl-D-aspartate receptor-associated encephalitis (NMDARE) is a rare immune-mediated neuroinflammatory condition characterized by the rapid onset of neuropsychiatric symptoms and autonomic dysfunction. The mechanism of pathogenesis remains incompletely understood, but is thought to be related to antibodies targeting the GluN1 subunit of the NMDA receptor with resultant downstream dysregulation of dopaminergic pathways. Young adults are most frequently affected; the median age at diagnosis is 21 years.

A Social Media Study on the Effects of Psychiatric Medication Use.

Understanding the effects of psychiatric medications during mental health treatment constitutes an active area of inquiry. While clinical trials help evaluate the effects of these medications, many trials suffer from a lack of generalizability to broader populations. We leverage social media data to examine psychopathological effects subject to self-reported usage of psychiatric medication.

Preconception Exposure to Fine Particulate Matter Leads to Cardiac Dysfunction in Adult Male Offspring.

Background Particulate matter (particles < 2.5 μm [ PM ]) exposure during the in utero and postnatal developmental periods causes cardiac dysfunction during adulthood. Here, we investigated the potential priming effects of preconception exposure of PM on cardiac function in adult offspring.

PM exposure in utero contributes to neonatal cardiac dysfunction in mice.

Objective: Exposure of fine particulate matter (PM) to pregnant dams has been shown to be strongly associated with adverse cardiovascular outcomes in offspring at adulthood, however, effects evident during neonatal periods are unclear. We designed this study to examine cardiac function of neonatal mice (14 days old) exposed to in utero PM.

Methods: Pregnant FVB female mice were exposed either to filtered air (FA) or PM at an average concentration of 91.

Social Media Participation in an Activist Movement for Racial Equality.

From the Arab Spring to the Occupy Movement, social media has been instrumental in driving and supporting socio-political movements throughout the world. In this paper, we present one of the first social media investigations of an activist movement around racial discrimination and police violence, known as "Black Lives Matter". Considering Twitter as a sensor for the broader community's perception of the events related to the movement, we study participation over time, the geographical differences in this participation, and its relationship to protests that unfolded on the ground.