Publications by authors named "Benjamin Nham"

Purpose: Number magnitude is often represented spatially in the mind by a mental number line, on which small numbers are located to the left of space and large numbers to the right. As vestibular dysfunction can affect aspects of spatial cognition, we wondered whether patients with acute vestibular loss would show a directional bias along the mental number line.

Methods: We gave 18 patients with vestibular neuritis (VN) (eight left VN, ten right; mean age 54 years, range 31-75 years; four females) and 15 normal age- and education-matched controls (mean age 47 years, range 26-75 years; 11 females) a mental number bisection task.

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Article Synopsis
  • The ocular vestibular evoked myogenic potential (oVEMP) measures how well the otolith organs function, primarily focusing on muscle responses elicited by sound stimuli.
  • The study examined the characteristics and pathways of late peaks in oVEMPs across different groups: healthy individuals, and patients with various levels of hearing and vestibular loss, using both bone and air-conducted stimuli.
  • Findings revealed that in healthy subjects, the initial waves were largest and predominantly contralateral, while patients with vestibular function could still produce late peaks, suggesting they originate from a different mechanism unrelated to hearing status.
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Objective: To examine the origin of cervical vestibular evoked myogenic potential (cVEMP) late waves (n34-p44) elicited with air-conducted click stimuli.

Design: Using a retrospective design, cVEMPs from normal volunteers were compared to those obtained from patients with vestibular and auditory pathologies.

Study Sample: (1) Normal volunteers (n = 56); (2) severe-to-profound sensorineural hearing loss (SNHL) with normal vestibular function (n = 21); (3) peripheral vestibular impairment with preserved hearing (n = 16); (4) total vestibulocochlear deficit (n = 23).

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Background: Vestibular migraine (VM) and Menière's disease (MD) are two common causes of recurrent spontaneous vertigo. Using history, video-nystagmography and audiovestibular tests, we developed machine learning models to separate these two disorders.

Methods: We recruited patients with VM or MD from a neurology outpatient facility.

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Objective: To examine the relationship between widely used otolith function tests: the Subjective Visual Horizontal (SVH) and Vestibular Evoked Myogenic Potentials (VEMP).

Methods: A retrospective analysis was performed on 301 patients who underwent SVH, ocular and cervical VEMP (oVEMP and cVEMP) tests on the same day. Correlations between the mean SVH tilt and amplitude asymmetry ratios for bone-conducted (BC) oVEMP and air-conducted (AC) cVEMP were examined.

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Object: Vestibular evoked myogenic potentials (VEMPs) and the subjective visual horizontal (SVH) (or vertical [SVV]) have both been considered tests of otolith function: ocular-VEMPs (oVEMPs) utricular function, cervical VEMPs (cVEMPs) saccular function. Some studies have reported association between decreased oVEMPs and SVH, whereas others have not.

Design: A retrospective study of test results.

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Article Synopsis
  • The study aimed to differentiate between posterior-circulation stroke (PCS) and vestibular-neuritis (VN) using quantitative vestibular tests conducted on patients within 72 hours of their hospital visit.
  • A total of 128 PCS and 134 VN patients were analyzed, revealing key differences in test results such as nystagmus patterns and severities, which were more pronounced in VN than in PCS.
  • The findings demonstrated that specific vestibular tests could reliably distinguish VN from PCS, achieving high sensitivity (92.9%) and specificity (89.8%), especially when combined with standard bedside assessments.
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Seventy Ménière's disease (MD) patients with spontaneous vertigo (100%), unilateral aural fullness (57.1%), tinnitus (78.6%), and subjective hearing loss (75.

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Objective: Many patients attending the emergency room (ER) with vertigo, leave without a diagnosis. We assessed whether the three tools could improve ER diagnosis of vertigo.

Methods: A prospective observational study was undertaken on 539 patients presenting to ER with vertigo.

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Background: We characterise the history, vestibular tests, ictal and interictal nystagmus in vestibular migraine.

Method: We present our observations on 101 adult-patients presenting to an outpatient facility with recurrent spontaneous and/or positional vertigo whose final diagnosis was vestibular migraine (n = 27) or probable vestibular migraine (n = 74). Ictal and interictal video-oculography, caloric and video head impulse tests, vestibular-evoked myogenic potentials and audiometry were performed.

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Objective: To separate vestibular neuritis (VN) from posteriorcirculation stroke (PCS) using quantitative tests of canal and otolith function.

Methods: Video Head-Impulse tests (vHIT) were used to assess all three semicircular canal pairs; vestibulo-ocular reflex (VOR) gain and saccade metrics were examined. Cervical and ocular-Vestibular-Evoked Myogenic Potentials (c- and oVEMP) and Subjective Visual Horizontal (SVH) were used to assess otolith function.

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The subjective visual horizontal (SVH) is a test of utricular function that assesses conjugate ocular torsion which is a component of the ocular tilt reaction (OTR). In unilateral destructive peripheral vestibular lesions, the OTR and so the SVH tilt is usually ipsiversive. Our study aimed to profile the causes of a contraversive SVH tilt in patients with a confirmed unilateral peripheral vestibular deficit.

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Vestibular-evoked myogenic potentials (VEMPs) are short-latency, otolith-dependent reflexes recorded from the neck and eye muscles. They are widely used in neuro-otology clinics as tests of otolith function. Cervical VEMPs are recorded from the neck muscles and reflect predominantly saccular function, while ocular VEMPs are reflexes of the extraocular muscles and reflect utricular function.

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