Generation of LexA enhancer-trap lines in Drosophila by an international scholastic network.

Conditional gene regulation in Drosophila through binary expression systems like the LexA-LexAop system provides a superb tool for investigating gene and tissue function. To increase the availability of defined LexA enhancer trap insertions, we present molecular, genetic, and tissue expression studies of 301 novel Stan-X LexA enhancer traps derived from mobilization of the index SX4 line. This includes insertions into distinct loci on the X, II, and III chromosomes that were not previously associated with enhancer traps or targeted LexA constructs, an insertion into ptc, and seventeen insertions into natural transposons.

Visual and cognitive demands of manual and voice-based driving mode implementations on smartphones.

Mobile phone apps and operating systems are increasingly adopting driving mode functions that attempt to reduce driver visual and cognitive demand by limiting functionality, using larger buttons and icons, and adding voice-based interactions. The present study assessed the visual and cognitive demands and the subjective level of distraction from two driving mode implementations (voice or manual) on an Android™ mobile phone using Google Assistant™, compared to a typical mobile phone operating system experience. While driving on a test track, participants performed several trials of five tasks on each of three interfaces: A mobile operating system interface, a manual driving mode interface, and a voice driving mode interface.

The Roelofs and induced Roelofs effects.

The visual image provides important cues for an observer's sense of location and orientation within the world. Occasionally, though, these cues can be misleading, resulting in illusions. In the Roelofs and induced Roelofs effects, for example, a large illuminated frame, offset from the observer's midline in otherwise complete darkness, tends to bias the observer's judgment of straight ahead, causing the position of the frame, and anything contained within it, to be misperceived.

Texting during stair negotiation and implications for fall risk.

Background/aim: Walking requires the integration of the sensory and motor systems. Cognitive distractions have been shown to interfere with negotiation of complex walking environments, especially in populations at greater risk for falls (e.g.

Active Listening Delays Attentional Disengagement and Saccadic Eye Movements.

Successful goal-directed visual behavior depends on efficient disengagement of attention. Attention must be withdrawn from its current focus before being redeployed to a new object or internal process. Previous research has demonstrated that occupying cognitive processes with a secondary cellular phone conversation impairs attentional functioning and driving behavior.

Individual differences in cognitive functioning predict effectiveness of a heads-up lane departure warning for younger and older drivers.

The effectiveness of an idealized lane departure warning (LDW) was evaluated in an interactive fixed base driving simulator. Thirty-eight older (mean age=77years) and 40 younger drivers (mean age=35years) took four different drives/routes similar in road culture composition and hazards encountered with and without LDW. The four drives were administered over visits separated approximately by two weeks to examine changes in long-term effectiveness of LDW.

PILOT RESULTS ON FORWARD COLLISION WARNING SYSTEM EFFECTIVENESS IN OLDER DRIVERS.

Advanced Driver Assistance Systems (ADAS) have largely been developed with a "one-size-fits-all" approach. This approach neglects the large inter-individual variability in perceptual and cognitive abilities that affect aging ADAS users. We investigated the effectiveness of a forward collision warning (FCW) with fixed response parameters in young and older drivers with differing levels of cognitive functioning.

EFFECTIVENESS OF A HEADS-UP ADAPTIVE LANE DEVIATION WARNING SYSTEM FOR MIDDLE-AGED & OLDER ADULTS.

46 participants (24 younger and 22 older) completed at least one out of four simulated drives designed to test the effectiveness of an Adaptive Lane Deviation Warning (LDW) system, and they drove through both a warnings-on and warnings-off version of each drive. Findings showed that LDW was effective in reducing reaction time for lane deviation corrections for both older (by 1.2 seconds) and younger drivers (by 1.

The role of the right superior parietal lobule in processing visual context for the establishment of the egocentric reference frame.

Visual cues contribute to the creation of an observer's egocentric reference frame, within which the locations and orientations of objects can be judged. However, these cues can also be misleading. In the rod-and-frame illusion, for example, a large tilted frame distorts the observer's sense of vertical, causing an enclosed rod to appear tilted in the opposite direction.

Shifts of visuospatial attention do not cause the spatial distortions of the Roelofs effect.

When a visible frame is offset left or right of an observer's objective midline, subjective midline is pulled toward the frame's center, resulting in an illusion of perceived space known as the Roelofs effect. However, a large frame is not necessary to generate the effect-even a small peripheral stimulus is sufficient, raising the possibility that the effect would be brought about by any stimulus that draws attention away from the midline. To assess the relationship between attention and distortions of perceived space, we adopted a paradigm that included a spatial cue that attracted the participant's attention, and an occasional probe whose location was to be reported.

Attentional control settings modulate susceptibility to the induced Roelofs effect.

When a visible frame is offset laterally from an observer's objective midline, the subjective midline is pulled toward the frame's center, causing the frame and any enclosed targets to be misperceived as being shifted somewhat in the opposite direction. This illusion, the Roelofs effect, is driven by environmental (bottom-up) visual cues, but whether it can be modulated by top-down (e.g.

Visual prior entry for foreground figures.

Attended stimuli reach perceptual-level processes before unattended stimuli do, a finding that is referred to as visual prior entry. We asked whether a similar effect arises for salient objects (foreground figures) in a visual scene. If prior entry holds for figure-ground perception, targets will be perceived to appear earlier on figures than on grounds.