Publications by authors named "Benjamin Leon-Mancilla"
Background: Cholecystectomy for conditions like iatrogenic injury during cholecystectomy can lead to complications such as bile duct injuries, necessitating alternative options like bioprosthesis.
Methods: This study evaluated a bioprosthesis's efficacy in maintaining bile duct continuity over 24 months in 16 male pigs.
Results: The bioprosthesis was implanted in the common bile duct of three-month-old animals, with follow-ups at 1, 6, 12, 18, and 24 months.
Hepatitis C virus-induced liver damage, chronic liver damage due to alcohol, and non-alcoholic liver disease-induced cellular alterations promote fibrosis, cirrhosis, and/or hepatocellular carcinoma. The recommended therapeutic option for advanced liver damage is liver transplantation. Extracellular matrix scaffolds have been evaluated as an alternative for tissue restoration.
View Article and Find Full Text PDFLiver diseases are the leading cause of death worldwide. Excessive alcohol consumption, a high-fat diet, and hepatitis C virus infection promote fibrosis, cirrhosis, and/or hepatocellular carcinoma. Liver transplantation is the clinically recommended procedure to improve and extend the life span of patients in advanced disease stages.
View Article and Find Full Text PDFIsaria fumosorosea (formerly Paecilomyces fumosoroseus) is an entomopathogenic fungus that has been proposed as a low risk environmental alternative to the use of chemical insecticides to control agricultural pests and disease vectors. Although there are some mycoinsecticides already being marketed in many countries, not all their biosafety protocols have been published. The acute dermal toxicity test in an animal model is one in a series of biosafety protocols that must be developed, in order to provide information on health hazards, while taking into consideration the periods that the workers are in direct contact with the microbial agent when applied for the control of pests.
View Article and Find Full Text PDFArticle Synopsis
- The study explored the effectiveness of a polymer-based absorbable bioprosthesis with bone scaffold in treating bile duct injuries in pigs following cholecystectomy.
- At three follow-up points (1, 3, and 6 months), no significant liver function changes or complications were observed, and imaging studies demonstrated no obstructions in the bile duct.
- The results indicated that the bioprosthesis successfully supported tissue regeneration, suggesting it could be a viable option for replacing the bile duct in cases of injury or cancer.
Background: "Surgical scrub" of the hands and arms is a fundamental procedure for reducing infection risk. We undertook this study in order to compare different antiseptics and their microbicidal effects, costs and times of the procedures.
Methods: Thirty students followed the surgical scrub procedure using benzalkonium chloride.
Background: Bone loss as a result of arthrodesis, pseudarthrosis, benign tumors and bone defects was treated using a xenoimplant (Nukbone).
Methods: The effectiveness of the material was evaluated through a longitudinal and observational study at the Hospital Regional "General Ignacio Zaragoza" (HRGIZ) ISSSTE. The Mexican xenoimplant is a patent of the National Autonomous University of Mexico (UNAM).