Background: After the 2009 influenza pandemic the H1N1pdm09 strain circulate seasonally. In 2015, Puerto Montt Hospital in Chile faced a simultaneous outbreak of both seasonal H3N2 and H1N1pdm09 influenza A (IA).
Aim: To evaluate the clinical differences between the two viral strains and recent changes in the behavior of H1N1pdm09 IA.