Fluorescein leakage of the optic disc: time course in primary open-angle glaucoma.

Purpose: To identify and quantify the time course of fluorescein leakage of the optic nerve head in primary open-angle glaucoma (POAG) and controls.

Methods: Twenty patients with POAG (aged 58 +/- 10 years) and 14 controls (aged 51 +/- 12 years, p = 0.07) were included in a prospective study.

Dronabinol and retinal hemodynamics in humans.

Purpose: To investigate the effects of oral cannabinoids on retinal hemodynamics assessed by video fluorescein angiography in healthy subjects.

Design: Interventional study.

Methods: In a self-experiment, the cannabinoid dronabinol (delta-9-tetrahydrocannabinol [THC]) was administered orally to eight healthy medical doctors (7.