Purpose: Periventricular nodular heterotopia (PVNH) is a malformation of cortical development due to impaired neuronal migration resulting in the formation of nodular masses of neurons and glial cells in close proximity to the ventricular walls. We report the clinical characteristics of the largest case series of FLNA-negative patients with seizures and bilateral periventricular heterotopia.
Methods: Participants were recruited through the Epilepsy Phenome/Genome Project (EPGP), a multicenter collaborative effort to collect detailed phenotypic data and DNA on a large number of individuals with epilepsy, including a cohort with symptomatic epilepsy related to PVNH.
Background Context: Screw fixation of the facet joint has been reported to stabilize the lumbar spine and facilitate spinal fusion. Accurate placement of translaminar facet screws (TLFSs) requires identification of the posterior spinal elements, and the facet joints in particular, which may be facilitated by intra-operative fluoroscopy.
Purpose: The purpose of this study was to define the radiographic parameters that will allow for successful placement of TLFSs.
Background Context: Laminoplasty provides an alternative to anterior procedures or multilevel laminectomy for patients with multilevel spinal stenosis and myeloradiculopathy.
Purpose: To review the techniques, results and complications of cervical laminoplasty.
Study Design: The three basic variations of laminoplasty are the single open door, the French door or midline and the Z-plasty technique.
Spine (Phila Pa 1976)
November 2002
Study Design: A literature review was conducted.
Objective: To provide an evidence-based approach for patients with neurogenic symptoms after lumbar surgery.
Summary Of Background Data: Patients may present with chronic pain of spinal origin after lumbar surgery.
Purpose: The purpose of this study was to determine the metabolic, histologic, and ultrastructural effects of morphine and its combination with saline and bupivacaine on human articular cartilage.
Type Of Study: In vitro study.
Methods: Nonfibrillated human articular cartilage was harvested and transferred into an experimental culture consisting of a control medium, saline, or a combination of morphine/saline or morphine/saline/bupivacaine for 12, 24, or 72 hours.
Study Design: Cadaver dissection and case reports were used to describe a novel technique of lumbar interbody arthrodesis that accesses the intervertebral disc through a posterolateral intertransverse process approach.
Objectives: To describe the surgical approach and technique required in performing an intertransverse lumbar interbody fusion. The clinical results in two patients with 2-year follow-up evaluation after intertransverse lumbar interbody fusion are reported.