ChemPix: automated recognition of hand-drawn hydrocarbon structures using deep learning.

Inputting molecules into chemistry software, such as quantum chemistry packages, currently requires domain expertise, expensive software and/or cumbersome procedures. Leveraging recent breakthroughs in machine learning, we develop ChemPix: an offline, hand-drawn hydrocarbon structure recognition tool designed to remove these barriers. A neural image captioning approach consisting of a convolutional neural network (CNN) encoder and a long short-term memory (LSTM) decoder learned a mapping from photographs of hand-drawn hydrocarbon structures to machine-readable SMILES representations.

Neurofibroma originating from a urachal mass.

Urachal anomalies are rare in the adult population and when diagnosed, are typically malignant. Herein, we report a case of a 61-year-old male who underwent an excision of a urachal mass for a presumed malignancy. Pathologic evaluation demonstrated a neurofibroma.

Review of Power Electronics Components at Cryogenic Temperatures.

In order to apply power electronics systems to applications such as superconducting systems under cryogenic temperatures, it is necessary to investigate the characteristics of different parts in the power electronics systems. This paper reviews the influence of cryogenic temperature on power semiconductor devices including Si and wide bandgap switches, integrated circuits, passive components, interconnection and dielectric materials, and some typical cryogenic converter systems. Also, the basic theories and principles are given to explain the trends for different aspects of cryogenically cooled converters.

Dependence of laser-induced tissue ablation on optical fiber movements for laser prostatectomy.

Purpose: The aim of the current study was to identify the efficient fiber movements for 532-nm laser prostatectomy.

Materials And Methods: 532-nm Lithium triborate (LBO) laser light was tested on 120 kidney tissues at three different translational speeds (TS 1, 2, and 4 mm/s) and four different rotational speeds (RS 0.5, 1.

Factors influencing drainage setting and cost for cutaneous abscesses among pediatric patients.

Objective: To evaluate the clinical and microbiological factors associated with skin and soft tissue infections drained in the emergency department (ED) vs operative drainage (OD) in a tertiary care children's hospital.

Methods: This was a cross-sectional study among children aged 2 months to 17 years who required incision and drainage (I&D). Demographic information, signs and symptoms, abscess size and location, and wound culture/susceptibility were recorded.

A retrospective review of office-based 532-nm GreenLight laser prostatectomy in men with symptomatic benign prostatic hyperplasia.

Objective: To evaluate the feasibility, safety, and outcomes of men with symptomatic benign prostatic hyperplasia undergoing 532-nm GreenLight laser prostatectomy in the office-based setting.

Materials And Methods: From September 2007 to October 2011, 47 patients underwent office-based 532-nm GreenLight laser prostatectomy by a single surgeon. Patients were enrolled prospectively and preoperative, intraoperative, and postoperative parameters were then reviewed retrospectively.

Evaluation of continence following 532 nm laser prostatectomy for patients previously treated with radiation therapy or brachytherapy.

Introduction/objective: Urinary complications such as bladder outlet obstruction or urinary retention following radiation therapy or brachytherapy have been reported in up to 15% of men. When conservative therapy has failed, surgical intervention with transurethral resection of the prostate (TURP) may be performed, but carries a significant risk of incontinence, ranging from 18% to 70% in reported literature. We reviewed a cohort of men previously treated with radiation or brachytherapy, who underwent laser prostatectomy.

Review of current laser therapies for the treatment of benign prostatic hyperplasia.

The gold standard for symptomatic relief of bladder outlet obstruction secondary to benign prostatic hyperplasia has traditionally been a transurethral resection of the prostate (TURP). Over the past decade, however, novel laser technologies that rival the conventional TURP have multiplied. As part of the ongoing quest to minimize complications, shorten hospitalization, improve resection time, and most importantly reduce mortality, laser prostatectomy has continually evolved.

Defining optimal laser-fiber sweeping angle for effective tissue vaporization using 180 W 532 nm lithium triborate laser.

Purpose: The goal of this study is to identify the most efficient sweeping angle (SA) during photoselective vaporization of the prostate (PVP).

Materials And Methods: Experiments were conducted with GreenLight XPS™ laser at 120 and 180 W. Ten blocks of porcine kidney were used for each SA (0, 15, 30, 45, 60, 90, and 120 degrees).

180-W XPS GreenLight laser therapy for benign prostate hyperplasia: early safety, efficacy, and perioperative outcome after 201 procedures.

Background: Photoselective vaporisation of the prostate has evolved from the GreenLight 80-W KTP powered laser to the latest 180-W XPS laser involving a MoXy fibre.

Objective: Evaluate the prevalence of perioperative complications and short-term outcome for the first time with the XPS laser in men with lower urinary tract symptoms (LUTS) due to benign prostatic enlargement (BPE).

Design, Setting, And Participants: Prospective data were collected from consecutive patients at seven centres worldwide during June 2010 and March 2011.

Optimal laser fiber rotational movement during photoselective vaporization of the prostate in a bovine ex-vivo animal model.

Background And Purpose: Photoselective vaporization of the prostate (PVP) has emerged as an effective debulking procedure for prostatic urinary obstruction. Surgical technique for the most efficient vaporization has, however, received little scientific investigation. We used an ex-vivo bovine prostate model to investigate how variation in the angle of laser fiber rotational movement ("sweeping") affects prostate tissue vaporization efficiency.

The effect of laser-fiber sweeping speed on the efficiency of photoselective vaporization of the prostate in an ex vivo bovine model.

Introduction: Recommendations for efficient photoselective vaporization of the prostate (PVP) include a side-to-side rotational laser-fiber "sweeping" motion, yet scientific study of this technique is lacking. We investigated whether the speed of laser-fiber sweeping affects tissue vaporization efficiency.

Methods: PVP was performed using the 120-W GreenLight high-performance system.

Evaluation of a new multi-basket load-release ureteral stent.

Introduction: A multi-basket ureteral stent was tested and modified to assess feasibility of load-release features intended to release stone(s) if resistance is encountered during stent removal.

Methods: Three versions of the stent were evaluated: (1) unaltered stent, (2) one strand of each basket partially cut to 50%, or 75% (3) tube between baskets longitudinally slit. One of the baskets was filled with multiple 3-4-mm stones or a single large 6-mm stone to 20Fr diameter.

Births using sperm retrieved via immediate microdissection of a solitary testis with cancer.

Objective: To determine the feasibility of achieving births using sperm retrieved from a solitary testis with cancer.

Design: Prospective clinical study of azoospermic men with testis cancer in a solitary testis.

Setting: Infertility patients in an academic environment.

Enhanced adenoviral-vector mediated gene transfer using human albumin solder.

Background And Objective: Laser tissue welding with human albumin solder (HAS) has been used as an alternative method of wound closure. Adenoviral vectors have been used to introduce various cytokine genes into wounds to accelerate wound closure. In the present study, we were interested in the effect of HAS on adenoviral vector transfer of the beta-galactosidase (beta-gal) gene in vitro and in vivo.

Pulmonary embolus related to PC-SPES use in a patient with PSA recurrence after radical prostatectomy.

Patients diagnosed with a rising prostate-specific antigen level after radical prostatectomy represent a therapeutic dilemma. Herbal therapies including PC-SPES have gained popularity as alternatives to conventional hormonal ablation in such patients as a result of the perceived benefits of using natural products and proven clinical response in decreasing prostate-specific antigen levels. PC-SPES is one of the most popular herbs with known estrogenic activity in vitro and in vivo.

A rare case of painless gross hematuria: primary localized AA-type amyloidosis of the urinary bladder.

A 60-year-old Asian woman presented with a 1-year history of painless gross hematuria. She had no prior urologic history and no other medical problems. Her physical examination, urine cytology, and computed tomography scan were normal.