[Vasopressin use in shock].

Arginine-vasopressin (VP), also known as the antidiuretic hormone, is essential for water homeostasis. Its synthesis and liberation depends on regulation of osmotic, hypovolemic, hormonal, and nonosmotic stimuli. It has been demonstrated that it is key for maintenance of cardiovascular homeostasis through vasomotor regulation, the determinant of systemic vascular resistance and mean arterial pressure, a process acting through V1 receptors.

[Vasopressin for treatment of shock].

Introduction: Vasodilatory refractory shock is common in patients with severe burns. It is defined by resistance to high doses of volume and vasopressor therapy.

Objective: Our objective was to investigate effects of vasopressin therapy in severe burn patients with vasodilatory refractory shock.