Postoperative bradycardia following adenotonsillectomy in children: Does intraoperative administration of dexmedetomidine play a role?

Introduction: Dexmedetomidine is a novel pharmacologic agent that has become a frequently used adjunct during care of pediatric patients with obstructive sleep apnea (OSA) undergoing tonsillectomy. While generally safe and effective, dexmedetomidine is associated with adverse effects of hypotension and bradycardia from its central sympatholytic effects. Due to safety concerns, our institution routinely admits patients with OSA for overnight cardiorespiratory monitoring following tonsillectomy.

Computational fluid dynamics evaluation of posterior septectomy as a viable treatment option for large septal perforations.

Background: Numerous surgical techniques exist to treat nasal septal perforation (NSP). The surgical closure of large NSPs (>2 cm) is still challenging. Posterior septectomy has been reported as a simple alternative to treat large NSP, yet its mechanisms for symptom relief are not clear, and if failed, its consequence cannot be easily reversed.

Anterior Segmental Osteotomy to Save Implants for Prosthetic Restoration: A Multidisciplinary Case Report.

Titanium root form dental implants are among the major advances modern dentistry can offer patients. Occasionally, in spite of all precautions and best operator intentions, implants are inadvertently placed in positions that do not permit their use for high-quality esthetic dental restorations. Salvaging these implants to permit their use is a challenge for practitioners.

Treatment of a recurrent ameloblastic fibroma.

Ameloblastic fibroma (AF), a slow-growing, benign tumor of odontogenic origin, represents 2% of all odontogenic tumors. Jaw expansion is among the most common symptoms, with diagnosis often made through routine radiographs. AFs have a recurrence rate of 18% to 43.

Management of Lateral Frontal Sinus Pathology in the Endoscopic Era.

Objectives: Considerable advances in endoscopic technique and experience have allowed an increasing number of patients with complex frontal sinus disease to be treated with endoscopic surgery. The objective of the current study was to evaluate management strategies and outcomes regarding treatment of lateral frontal sinus disease.

Study Design: Prospective case series.

Salvage surgery for recurrent cancers of the oropharynx: comparing TORS with standard open surgical approaches.

Importance: Surgical salvage may be the only viable treatment option for recurrent tumors of the oropharynx. To our knowledge, there have been no published reports directly comparing the oncologic and functional outcomes of patients with recurrent oropharyngeal squamous cell carcinoma (SCC) treated with transoral robotic-assisted surgery (TORS) with those treated with traditional open surgical approaches.

Objective: To compare the oncologic and functional outcomes of patients with recurrent oropharyngeal SCC treated with TORS with those treated with traditional open surgical approaches.

CD147 and AGR2 expression promote cellular proliferation and metastasis of head and neck squamous cell carcinoma.

The signaling pathways facilitating metastasis of head and neck squamous cell carcinoma (HNSCC) cells are not fully understood. CD147 is a transmembrane glycoprotein known to induce cell migration and invasion. AGR2 is a secreted peptide also known to promote cell metastasis.