Publications by authors named "Benijts J"

Article Synopsis
  • The study compares the two-year functional and oncological outcomes of Retzius-sparing robot-assisted laparoscopic prostatectomy (rsRALP) vs. standard robot-assisted laparoscopic prostatectomy (sRALP) in patients with localized prostate cancer.
  • Results show that rsRALP significantly improves urinary function and quality of life over time, while sexual function differences were negligible after 12 months.
  • Although rsRALP had some negative surgical margin characteristics, it did not affect biochemical recurrence rates after five years, indicating no significant difference in long-term oncological outcomes between the two methods.
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Article Synopsis
  • - This study assessed patients with PI-RADS 3 lesions from mpMRI to improve risk assessment for clinically significant prostate cancer (csPCa) prior to biopsy.
  • - A total of 790 patients with PI-RADS 3 lesions were analyzed, revealing that 19% had csPCa, with significant associations noted for age and PSA density (PSAd).
  • - Results suggest that if a patient's PSAd is below 0.13 ng/ml/cc, especially below 0.09 ng/ml/cc, prostate biopsies may be safely avoided, reducing unnecessary procedures and the risk of overdiagnosis.
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Background And Objective: A notable paradigm shift has emerged in the choice of prostate biopsy approach, with a transition from transrectal biopsy (TRBx) to transperineal biopsy (TPBx) driven by the lower risk of severe urinary tract infections. The impact of this change on detection of clinically significant prostate cancer (csPCa) remains a subject of debate. Our aim was to compare the csPCa detection rate of TRBx and TPBx.

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Purpose: To describe our technique of nerve sparing laparoscopic radical prostatectomy (LRP). We present the oncological and functional results (potency and urinary continence).

Material And Methods: LRP has become standard at our institution based on experience with more than 2800 consecutive cases operated on between 1997 and 2005.

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Article Synopsis
  • The study evaluated complications, voiding patterns, and quality of life in 58 patients who underwent orthotopic bladder substitution using an N-shaped ileal neobladder after radical cystectomy.
  • The findings revealed that 38% experienced early complications, mostly diarrhea, while 48% faced late complications, with ileo-urethral stenosis being the most common pouch-related issue.
  • Despite the complications, the majority of patients achieved daytime (95%) and nighttime (66%) continence, and the overall impact on quality of life was deemed acceptable, though diarrhea remained a significant discomfort.
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Intracytoplasmic sperm injection of immotile (dead) ejaculated human spermatozoa has been carried out by several centres for the treatment of infertility caused by severe asthenozoospermia (necrozoospermia). No healthy pregnancies have been reported as yet, suggesting irreversible damage to sperm DNA, centrioles and/or other important structures. We investigated this hypothesis by injection of immotile human spermatozoa obtained from several male infertility patients into mouse oocytes and analysis of the oocyte activation rate and sperm chromosome integrity.

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