Publications by authors named "Benifla J"

Background: Sentinel lymph node biopsy (SLNB) is commonly used in the surgical management of male breast cancer. Contrary to female breast cancer, limited data exist about its performance in male breast cancer. The objective of this systematic review and meta-analysis was to evaluate the SLNB accuracy in male breast cancer.

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  • - This study (BZK40+) investigated the effectiveness and safety of a spermicide containing benzalkonium chloride in women aged 40 and above, aiming to assess its contraceptive efficacy over 12 months.
  • - A total of 151 women participated, with a high retention rate; 95.4% completed the initial 6-month phase, and 41.7% opted to continue for another 6 months, applying the spermicide in 96.3% of their sexual encounters.
  • - Remarkably, the study reported a Pearl Index of 0 pregnancies during the 12-month period, indicating effective contraception, but the authors suggest caution in interpreting these results due to the usual lower efficacy of spermicides
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Background: Lymphadenectomy is part of cytoreductive surgery for patients with advanced epithelial ovarian cancer (AEOC) in case of abnormal lymph nodes before and during surgery. The aim of this study was to develop and validate a pre-operative radiological score to predict pelvic and/or para-aortic lymph node metastasis (LNM) in patients with AEOC undergoing cytoreductive surgery.

Methods: We conducted a multicentre retrospective study.

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Background: Miscarriage is a frequent problem that requires dilation and curettage in 30% of cases. This routine surgery may lead to intrauterine adhesions and severe infertility. Hyaluronic acid gel is known to reduce intrauterine adhesions after hysteroscopic surgery.

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In advanced epithelial ovarian cancer (EOC), the LION trial restricted lymphadenectomy indication to patients with suspect lymph nodes before and during surgery. Preoperative imaging is used to assess lymph node status, and particularly CT and PET/CT. The aim of this systematic review and meta-analysis was to evaluate the diagnostic accuracy of preoperative CT and PET/CT to detect lymph node metastasis (LNM) in patients with EOC; Methods: Databases were searched from January 1990 to May 2019 for studies that evaluated the diagnostic accuracy of preoperative CT and PET/CT to detect LNM in patients with EOC with histology as the gold standard.

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Objective: The aim of this study was to develop a new diagnostic tool to predict lymph node metastasis (LNM) in patients with advanced epithelial ovarian cancer undergoing primary cytoreductive surgery.

Materials And Method: The FRANCOGYN group's multicenter retrospective ovarian cancer cohort furnished the patient population on which we developed a logistic regression model. The prediction model equation enabled us to create LNM risk groups with simple lymphadenectomy decision rules associated with a user-friendly free interactive web application called shinyLNM.

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Introduction: Para-aortic lymphadenectomy plays a fundamental role in the surgical management of pelvic gynecological cancers. Two laparoscopic approaches exist: the transperitoneal (TP) and the extraperitoneal (EP). The aim of this study was to compare these 2 approaches in terms of surgical outcomes, specially the number of removed lymph nodes according to the surgical technique, and morbidity.

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Breast cancer is the leading cause of cancer death in women, and most breast cancer related deaths are due to metastases. Uterine metastases from breast cancer are uncommon and rarely reported in the literature. We described the case of a 50 years-old-woman who developed a uterine metastasis, 6 years after the diagnosis of an invasive ductal breast carcinoma.

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After the publication of the Lymphadenectomy in Ovarian Neoplasms (LION) trial results, lymphadenectomy in advanced epithelial ovarian cancer with primary complete cytoreductive surgery is considered indicated only for women with suspicious lymph nodes. The aim of this meta-analysis was to evaluate the diagnostic accuracy of intraoperative clinical examination for detecting lymph node metastases in patients with advanced epithelial ovarian cancer during primary complete cytoreductive surgery. MEDLINE, EMBASE, Web of Science and the Cochrane Library were searched for January 1990 to May 2019 for studies evaluating the diagnostic accuracy of intraoperative clinical examination for detecting lymph node metastases in patients with advanced epithelial ovarian cancer during primary complete cytoreductive surgery, with histology as the gold standard.

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Background/aim: Fibroepithelial lesions (FEL) of the breast include fibroadenomas and phyllodes tumors (PT). Their histologic characteristics on core needle biopsy can overlap, while their clinical management is different. The aim of this study was to develop and to validate a pre-operative score for the diagnosis of PT with surgical decision rules.

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We report a case of cesarean scar pregnancy at 16 weeks. Magnetic resonance imaging confirmed the isthmic ectopic location with an empty fundus and a high suspicion of placental invasion to the anterior myometrium. Because of pelvic pain, bleeding and the major risks of hysterectomy, a decision was made to terminate the pregnancy.

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Neuropathological conditions might affect adult granulogenesis in the adult human dentate gyrus. However, radial glial cells (RGCs) have not been well characterized during human development and aging. We have previously described progenitor and neuronal layer establishment in the hippocampal pyramidal layer and dentate gyrus from embryonic life until mid-gestation.

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Objectives: To evaluate feasibility of performing benign gynecologic pathology low pressure (7mmHg) laparoscopy (LPL) with AirSeal system and to study benefits in terms of postoperative pain, when compared to a standard insufflation group (15mmHg).

Materials And Methods: In this prospective randomized pilot study, 60 patients had laparoscopy for gynecologic benign pathology: 30 with 7mmHg and AirSeal system, and 30 with 15mmHg standard insufflator. The primary endpoint was incidence of shoulder pain.

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Postpartum lower limb motor and/or sensory deficit is an uncommon obstetrical complication. We aimed to identify its incidence, etiology, and precipitating factors, as well as the neurological prognosis by retrospectively analyzing the successive neurological evaluations, electrophysiological, and MRI data from all the consecutive patients with postpartum motor and/or sensory deficits of the lower limbs referred from the Lariboisière Obstetrical Department to the Lariboisière Neurophysiology Department, from January 2012 to June 2016, as well as data concerning labor and morphological characteristics of mother and baby. Thirteen patients (0.

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Background: The risk of vertical transmission of hepatitis B virus (HBV) increases as maternal HBV DNA increase, despite serovaccination to newborns.

Methods: From 1 July 2012 to 1 January 2016, all pregnant women in Lariboisiere Hospital, Paris, France, with HBV DNA of 5 log10 IU/ml and above were administered tenofovir from week 28 of pregnancy until delivery. HBV DNA was measured at months 1, 2 of tenofovir and at delivery.

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Article Synopsis
  • Couples can be considered infertile if they don't conceive after 12 months of unprotected intercourse, with various factors contributing to infertility rates among males and females worldwide.
  • The study evaluated pregnancy outcomes from in-vitro fertilization (IVF) compared to natural conception in Douala, Cameroon, involving 102 women; 51 conceived via IVF and 51 naturally.
  • Results indicated that women conceived through IVF had significantly higher rates of cesarean deliveries, multiple pregnancies, and a greater likelihood of being first-time mothers compared to those who conceived naturally.
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  • The study evaluated the hepatitis B virus (HBV) status of children born to women who were coinfected with HIV and HBV, focusing on those who had access to antiretroviral therapy from 2000 to 2012.
  • Out of 35 children studied, 74% developed protective antibodies against HBV after receiving HBV immunoglobulin and vaccines, indicating that maternal treatment with lamivudine or tenofovir/emtricitabine during pregnancy was effective.
  • No child showed signs of chronic HBV infection, but there were instances of incomplete vaccination and uncertainty about immunoglobulin receipt, underscoring the need for larger studies to assess long-term vaccine protection.
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Objective: To assess the benefits of a multidisciplinary care among excised women with an initial surgery project and identify the reasons for discarding surgery.

Methods: Descriptive and retrospective study performed between the 1st of January 2006 and the 31st of December 2011 at the Armand Trousseau Hospital, Paris. All excised patients went through consultations with a mid-wife, a sexologist, a psychologist, a gynaecologist-obstetrician and, for some of them, underwent a clitoral reconstructive surgery.

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  • The study investigates Hepatitis B Virus (HBV) Mother-To-Child Transmission (MTCT) among HIV/HBV co-infected women, which has been less studied compared to HIV MTCT.
  • Out of 530 HIV-infected women, 49 were co-infected, with 34 giving birth to 57 children during the study period; follow-up data were available for 21 women and their 35 children.
  • Results showed that 74.3% of the children had protective HBV antibodies, with a significant correlation between receiving immunoglobulin at birth, complete vaccination, and positive outcomes against HBV.
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Objective: The objective of this multicenter, randomized study was to investigate the efficacy of the hydrophilic resorbable film PREVADH™ in preventing postoperative adhesions following myomectomy.

Study Design: Women scheduled for laparotomic myomectomy with intramural and/or subserous myomas of >60mm in diameter, and who wished to preserve fertility, were eligible. Patients were randomized immediately prior to abdominal wall closure to receive either hydrophilic resorbable film applied directly to the incisions (P-Group, n=33) or 500mL Ringer's lactate solution instilled into the pelvic cavity (R-Group, n=28).

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  • A study was conducted to compare the risk of major birth defects in children conceived through standard ICSI versus morphologically selected sperm ICSI (IMSI) between 2005 and 2010.
  • The study involved 1,028 infants and found that major malformations occurred significantly less in the IMSI group (1.33%) compared to the ICSI group (3.80%).
  • The results suggest that selecting sperm before ICSI may lower the risk of birth defects, particularly in boys, highlighting the potential benefits of using IMSI.
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