Acupuncture upregulates G protein coupled activity in SAMP8 mice.

Background: Transmembrane and intracellular signal transduction of G protein is closely related to the pathophysiology of Alzheimer's disease (AD).

Objective: To explore the effects of acupuncture on G protein signal transduction pathways in the pathogenesis of AD.

Methods: 36 senescence-accelerated (SAM) prone 8 mice were divided into three groups that remained untreated (SAMP8, n=12) or received acupuncture (SAMP8+SA, n=12) or control acupuncture (SAMP8+CA, n=12).

Computational investigation of a new ion-pair receptor for calix[4]pyrrole.

Theoretical studies of a new ion-pair receptor, meso-octamethylcalix[4]pyrrole (OMCP), and its interactions with the halide anions F(-), Cl(-), and Br(-) and the cesium halides CsF, CsCl, and CsBr have been performed. Geometries, binding energies, and binding enthalpies were evaluated with the restricted hybrid Becke three-parameter exchange functional (B3LYP) method using the 6-31+G(d) basis set and relativistic effective core potentials. The optimized geometric structures were used to perform natural bond orbital (NBO) analysis.

Cervical spondylosis treated by acupuncture at Ligou (LR 5) combined with movement therapy.

Objective: To compare therapeutic effects of acupuncture at Ligou (LR 5) plus movement therapy and conventional acupuncture on cervical spondylosis.

Methods: The therapeutic effect of acupuncture at Ligou (LR 5) plus movement therapy on 57 cases of cervical spondylosis (Group Acup.+M) was observed and compared with that of conventional acupuncture (Group Acup.

[Effects of different acupuncture treatment on mean blood flow velocity of middle cerebral artery on the affected side and rehabilitation of hemiparalysis caused by cerebral infarction].

Objective: To observe the effects of two different acupuncture treatment on cerebral blood flow velocity and early rehabilitation of hemiparalysis caused by cerebral infarction.

Methods: Eighty patients were randomly divided into an alternate acupuncture group (n = 40) and a routine acupuncture group (n = 40). Both of the groups were treated with routine neurology medicine and application of good limb position combined with acupuncture.

[Optimum selection of acupuncture treatment programs of cerebral infarction and its effects on insulin resistance].

Objective: To study the optimum acupuncture treatment program and the mechanism for treatment of cerebral infarction.

Methods: Sixty-three cases were randomly divided into 9 groups. The four factors, times of manipulation, the retaining time of the needle, acupuncture instrument and acupoints,and their corresponding three levels were adopted respectively in treatment of each group.