Molecular characterization and B-cell epitope analysis of the TSP11 gene in infection strains from Yunnan Province.

This study investigates the molecular intricacies of the transmembrane protein TSP11 gene in strains isolated from livestock and patients in Yunnan Province afflicted with between 2016 and 2020. Gene typing analysis of the ND1 gene revealed the presence of the G1 type, G5 type and untyped strains, constituting 52.4, 38.

Occurrence rate and species and subtypes of Cryptosporidium spp. in pet dogs in Yunnan Province, China.

Background: Cryptosporidium spp. is a ubiquitous, globally distributed intestinal protozoan infecting humans and at least 260 animal hosts. Due to close human contact with pet dogs and identification of zoonotic Cryptosporidium species and subtypes in these animals, dog health is not only a veterinarian issue but also a public health issue.

Occurrence and genetic characterization of Enterocytozoon bieneusi in pet dogs in Yunnan Province, China.

Enterocytozoon bieneusi is the most common microsporidian species in humans and can affect over 200 animal species. Considering possible increasing risk of human E. bieneusi infection due to close contact with pet dogs and identification of zoonotic E.

Agarose Hydrogel-Boosted One-Tube RPA-CRISPR/Cas12a Assay for Robust Point-of-Care Detection of Zoonotic Nematode Anisakis.

Rapid and accurate detection of the zoonotic nematode Anisakis is poised to control its epidemic. The clustered regularly interspaced short palindromic repeats (CRISPR)/Cas-associated assay shows great potential in the detection of pathogenic microorganisms. The one-tube method integrated the CRISPR system with the recombinase polymerase amplification (RPA) system to avoid the risk of aerosol pollution; however, it suffers from low sensitivity due to the incompatibility of the two systems and additional manual operations.

Analysis of Epidemiological and Issues Encountered in Case Reports on Echinococcosis - China, 2022.

What Is Already Known About This Topic?: Echinococcosis is classified as a Class C infectious disease in China. It is endemic in 370 counties located in the agricultural and pastoral regions of western China.

What Is Added By This Report?: This report provides a comprehensive overview of the cases of echinococcosis reported in China in 2022.

First survey of Enterocytozoon bieneusi and dominant genotype Peru6 among ethnic minority groups in southwestern China's Yunnan Province and assessment of risk factors.

Background: Enterocytozoon bieneusi is the most common microsporidian species causing diarrhea and other intestinal disorders in humans and animals. Like other infectious diseases, microsporidiosis usually disproportionately affects poor populations. In China, some ethnic minority areas remain poor.

Malaria control along China-Myanmar Border during 2007-2013: an integrated impact evaluation.

Background: Implementing effective interventions remain a lot of difficulties along all border regions. The emergence of artemisinin resistance of Plasmodium falciparum strains in the Greater Mekong Subregion is a matter of great concern. China has effectively controlled cross-border transmission of malaria and artemisinin resistance of P.

Dynamic positron emission tomography restoration with low-rank representation incorporating edge preservation.

Background: Dynamic positron emission tomography (PET) is a powerful tool that provides useful quantitative information on physiological and biochemical processes. However, the low signal-to-noise ratio (SNR) in short dynamic frames is a challenge.

Objective: To get high SNR in the dynamic PET and to achieve high-quality PET parametric image are the objective of this study.

[Survey on Malaria Epidemics in China-Myanmar Border Area].

The malaria epidemics in Laza city of Myanmar and Yingjiang county in Yunnan province of China in 2012 and 2013 was reviewed retrospectively, and a survey on malaria infection was conducted in residents in the border areas. A total of 179 malaria cases were reported in Yingjiang county from 2012 to 2013, with an average annual incidence of 2.9 per 10,000.

[Comparison between the head-chest leads electrocardiogram and routine leads in the manifest accessory pathways in patients with Wolff-Parkinson-White syndrome].

Objective: To observe whether there was difference between the head-chest leads electrocardiogram (HCECGs) and routine lead electrocardiogram (RLECGs) in the manifest accessory pathways in patients with Wolff-Parkinson-White syndrome.

Methods: HCECGs and RLECGs were recorded simultaneously in patients with Wolff-Parkinson-White syndrome, whose manifest accessory pathways had been confirmed by radiofrequency catheter ablation and intra-cardiac electrophysiology according to the same standard set beforehand. The diagnosis of pathways location was made by analysis of each HCECG and RLECG by two senior physicians in clinical electrophysiology.

[Relationship between reference point potential and potential distribution of normal electrocardial field on the thoracic surface of healthy individuals].

Objective: To explore the effect of reference point on the potential distribution of normal cardioeleclric field of healthy individuals.

Methods: Two different reference points including central terminal and right forehead were applied to record electrocardiogram simultaneously from 15 testing points (V(1)-V(6), V(7)-V(9), V(3R)-V(8R)) of Wilson lead (RL) and the same testing points (HV(1)-HV(9), HV(3R)-HV(8R)) of head-chest (HC) lead around the torso of healthy individuals. Chi-square test was performed to observe statistical difference between the HCECGs and RLECGs according to different shapes of QRS and T waves.

[Evaluation of resultant cardiac vector based on voltage distribution of electrocardial field around ex vivo guinea pig heart].

Objective: To evaluate the possibility of resultant cardiac vector of ex vivo guinea pig heart.

Methods: ECGs were recorded in 4 directions on every plane, and in each direction 4 points at different distances from the anterior, posterior, right and left of isolated guinea pig ventricles immersed in normal saline and distilled water.

Results: Main upward waves of ECGs were recorded at all points in 4 directions at 3 levels in the two media.

[Comparison of head-chest lead electrocardiogram and routine lead electrocardiogram in diagnosis of acute posterior wall myocardial infarction].

Objective: To compare the value of head-chest lead electrocardiogram (HCECG) and routine lead electrocardiogram (RLECG) in diagnosis of acute positive posterior myocardial infarction.

Methods: HCECGs and RLECGs were recorded simultaneously in 68 normal individuals and 32 patients with acute posterior wall myocardial infarction confirmed by coronary angiography and echocardiography. Each HCECG and RLECG was analyzed by two senior physicians specialized in clinical electrophysiology who were blinded to the results.

[An efficient method for simulating ventricular electrical activity based on anatomic structure by incorporating AP model].

Conventional medical experiments can hardly simulate cardiac excitation propagation and observe the evolvement of cardiac electrical activities firsthand as is possible with computer simulation. Based on the anatomic structure of the heart, simulation of cardiac electrical activity mainly consists of the emulation of the excitation process among the cardiac cells and calculation of the electrical activities of individual cardiac cells. In this study we establish a geometric ventricular structure model demonstrating the direction of the cardiac muscle fibers and the layers of the ventricular cells, and endow different action potential models to the ventricular cells of different layers, and observe the activation process of the ventricular parts in view of the three-dimensional anatomy.

Truth telling in medicine: the Confucian view.

Truth-telling to competent patients is widely affirmed as a cardinal moral and biomedical obligation in contemporary Western medical practice. In contrast, Chinese medical ethics remains committed to hiding the truth as well as to lying when necessary to achieve the family's view of the best interests of the patient. This essay intends to provide an account of the framing commitments that would both justify physician deception and have it function in a way authentically grounded in the familist moral concerns of Confucianism.

[Fast elimination of 50-Hz noise in PC-based application system].

The interference by 50-Hz noise arising from the power supply cables is common in PC-based application system, often considerably affecting the detection of useful signals. On the basis of self-adapting correlation method, we attempt to address the problem of fast elimination of 50-Hz noise from the useful signals in PC-based application system such as digital ECG recording system.