Accelerated white matter lesion analysis based on simultaneous and quantification using magnetic resonance fingerprinting and deep learning.

Purpose: To develop an accelerated postprocessing pipeline for reproducible and efficient assessment of white matter lesions using quantitative magnetic resonance fingerprinting (MRF) and deep learning.

Methods: MRF using echo-planar imaging (EPI) scans with varying repetition and echo times were acquired for whole brain quantification of and in 50 subjects with multiple sclerosis (MS) and 10 healthy volunteers along 2 centers. MRF and parametric maps were distortion corrected and denoised.

Magnetic resonance fingerprinting for simultaneous renal T and mapping in a single breath-hold.

Purpose: To evaluate the use of magnetic resonance fingerprinting (MRF) for simultaneous quantification of and in a single breath-hold in the kidneys.

Methods: The proposed kidney MRF sequence was based on MRF echo-planar imaging. Thirty-five measurements per slice and overall 4 slices were measured in 15.

Time efficient whole-brain coverage with MR Fingerprinting using slice-interleaved echo-planar-imaging.

Magnetic resonance fingerprinting (MRF) is a promising method for fast simultaneous quantification of multiple tissue parameters. The objective of this study is to improve the coverage of MRF based on echo-planar imaging (MRF-EPI) by using a slice-interleaved acquisition scheme. For this, the MRF-EPI is modified to acquire several slices in a randomized interleaved manner, increasing the effective repetition time of the spoiled gradient echo readout acquisition in each slice.

Temporally resolved parametric assessment of Z-magnetization recovery (TOPAZ): Dynamic myocardial T mapping using a cine steady-state look-locker approach.

Purpose: To develop and evaluate a cardiac phase-resolved myocardial T mapping sequence.

Methods: The proposed method for temporally resolved parametric assessment of Z-magnetization recovery (TOPAZ) is based on contiguous fast low-angle shot imaging readout after magnetization inversion from the pulsed steady state. Thereby, segmented k-space data are acquired over multiple heartbeats, before reaching steady state.

Magnetic resonance fingerprinting using echo-planar imaging: Joint quantification of T and T2∗ relaxation times.

Purpose: To develop an implementation of the magnetic resonance fingerprinting (MRF) paradigm for quantitative imaging using echo-planar imaging (EPI) for simultaneous assessment of T and T2∗.

Methods: The proposed MRF method (MRF-EPI) is based on the acquisition of 160 gradient-spoiled EPI images with rapid, parallel-imaging accelerated, Cartesian readout and a measurement time of 10 s per slice. Contrast variation is induced using an initial inversion pulse, and varying the flip angles, echo times, and repetition times throughout the sequence.