Publications by authors named "Benedikt Peter"
Article Synopsis
- The study aimed to explore differences in characteristics and 2-year outcomes after surgical aortic valve replacement (SAVR) between males and females, using data from two registries involving 933 patients.
- Females had certain clinical differences such as lower body mass index, higher surgical risk scores, and smaller valves compared to males, but these disparities largely disappeared after adjusting for similar baseline characteristics.
- Ultimately, despite a higher initial surgical risk profile, both sexes had comparable outcomes 2 years post-SAVR, indicating no significant differences in overall results based on sex.
Objectives: Although the Perceval sutureless aortic valve bioprosthesis presents a feasible alternative to conventional aortic valve prostheses, the extent of its applicability with respect to technical considerations for a real-world patient collective is still under debate.
Methods: One hundred patients received the Perceval prosthesis [males: 59; age: 72.5 (7.
Article Synopsis
- Growth and division of biological cells rely on complex reactions driven by proteins, but how early cells inherited components before proteins is still unclear.
- This study uses ribozymes, which are catalytic RNA molecules, to show that freezing and thawing solutions can convert inactive RNA precursors into active ribozymes within lipid vesicles.
- The findings suggest that the cyclic process of freezing and melting, likely present on early Earth, could have allowed early protocells to grow and divide while still enabling the replication of RNA inside new vesicles.
Article Synopsis
- Compartmentalization is essential for cellular processes, allowing biomolecules to interact at the right times and places through self-organization of lipids, nucleic acids, and proteins.
- By utilizing reversible RNA-based liquid-liquid phase separation within giant unilamellar vesicles, researchers developed a system that propagates RNA enzymatic reactions through freeze-thaw cycles.
- This study shows that condensation of RNA can speed up enzymatic reactions and that decondensed RNA allows for exchange of materials between vesicles, paving the way for controlled processes in minimal cell models.
Introduction: The frozen elephant trunk technique (FET) has become routine for aortic arch and descending aortic repair. New hybrid prosthesis models are constantly being developed to increase effectiveness and durability of aortic repair. Recently, concerns were raised regarding increased post-operative bleeding using a new-generation hybrid prosthesis (E-vita OPEN NEO, CryoLife Inc.
View Article and Find Full Text PDFBackground: Degenerative aortic valve disease accounts for 10-20% of all cardiac surgical procedures. The impact of pre-existing comorbidities on the outcome of patients undergoing surgical aortic valve replacement (SAVR) needs further research.
Methods: The IMPACT registry is a non-interventional, prospective, open-label, multicenter, international registry with a follow-up of 5 years to assess the impact of pre-existing comorbidities of patients undergoing SAVR with the INSPIRIS RESILIA aortic valve on outcomes.
Research on the origin of life is highly heterogeneous. After a peculiar historical development, it still includes strongly opposed views which potentially hinder progress. In the 1st Interdisciplinary Origin of Life Meeting, early-career researchers gathered to explore the commonalities between theories and approaches, critical divergence points, and expectations for the future.
View Article and Find Full Text PDFDouble-arterial cannulation during aortic arch reconstruction in pediatric patients.
Multimed Man Cardiothorac Surg
December 2018
Aortic arch reconstruction is a highly demanding procedure in congenital heart surgery. The 2 conventional options for cardiopulmonary bypass - deep hypothermic circulatory arrest or antegrade cerebral perfusion - both result in lack of perfusion of the entire or lower body. In 2003, the Children's Heart Center Linz started to use a double-arterial cannulation technique for aortic arch reconstructions in order to provide whole body perfusion during the entire operation.
View Article and Find Full Text PDFObjectives: Patients with severe left ventricular outflow tract obstruction often suffer from impaired left ventricular function, endocardial fibroelastosis and borderline-sized structures. The early Ross-Konno operation can offer complete repair due to outflow tract stenosis and enable the functional recovery and growth of small structures.
Methods: Between 2008 and March 2017, 44 early Ross-Konno procedures were performed at our centre.
N-doped carbon materials are discussed as catalyst supports for the electrochemical oxygen reduction reaction (ORR) in fuel cells. This work deals with the preparation of Pt nanoparticles (NPs) supported on N-doped carbon nanofibers (N-CNF) from a polyaniline nanofiber (PANI NF) precursor, and investigates the ORR activity of the produced materials. Initially, Pt NPs are deposited on PANI NFs.
View Article and Find Full Text PDFMitral valve repair using autologous leaflet tissue as neochordae.
J Thorac Cardiovasc Surg
November 2014
The purpose of this study was to report the learning curve of endovascular aneurysm repair (EVAR) based on the Zenith stent graft (Cook Medical Inc., Bloomington, IN). In the last 9 years, 101 patients were treated with a Zenith stent graft.
View Article and Find Full Text PDFSelf-retaining pledgeted suture as retractor for mitral procedure.
Asian Cardiovasc Thorac Ann
April 2009
A simple reliable maneuver to optimize exposure of the left atrium for mitral valve operations is described. It offers more space to mobilize the valvular structure, facilitating complicated reconstruction in the posteromedial commisural area.
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