Publications by authors named "Benedicte Fremy"
Aim: To investigate the association between routine use of dipeptidyl peptidase-4 (DPP-4) inhibitors and the severity of coronavirus disease 2019 (COVID-19) infection in patient with type 2 diabetes in a large multicentric study.
Materials And Methods: This study was a secondary analysis of the CORONADO study on 2449 patients with type 2 diabetes (T2D) hospitalized for COVID-19 in 68 French centres. The composite primary endpoint combined tracheal intubation for mechanical ventilation and death within 7 days of admission.
Article Synopsis
- * Analysis was conducted on 1,965 patients from the CORONADO study, categorizing them into normal weight, overweight, and various obesity classes, revealing significant risks associated with higher BMI for intubation and death by day 7.
- * The findings suggest that while overweight and obesity worsen early COVID-19 prognosis in T2D patients, this negative effect is not observed in patients aged 75 and older, indicating a need for tailored management strategies for older adults.