Publications by authors named "Benedict Kaiser"
Objective: This phase I clinical trial assessed the use of autologous nasal chondrocyte tissue-engineered cartilage (N-TEC) for functional repair of nasal septal perforations (NSP).
Background: The most widely used technique to treat NSP, namely interposition grafting with a polydioxanone (PDS) plate combined with a deep temporal fascia (DTF) graft, is still suboptimal towards patient satisfaction and revision rates.
Methods: Patients ( n =5, all female, age range: 23-54 years) had a 0.
Article Synopsis
- A study evaluated the effectiveness of using vascularized bone grafts from the medial femur condyle to repair small bone defects (< 4 cm) in the upper extremity, excluding the scaphoid.
- Eight grafts were used in 7 patients, focusing on healing, complications, donor site issues, and patient satisfaction over a follow-up period of 3 to 40 months.
- Results showed successful bony healing in 4 cases, delayed healing in 3, and one case of partial healing, with high patient satisfaction reported overall.
Article Synopsis
- Lobular capillary hemangioma (LCH), also known as pyogenic granuloma, is a common but benign tumor characterized by a network of capillaries, affecting various types of tissue.
- A 26-year-old female developed a slow-growing infraorbital mass following a closed rhinoplasty, but the mass was not painful, only causing a feeling of pressure.
- After excisional biopsy confirmed a rare subcutaneous intravascular LCH, the patient showed no signs of recurrence after 3 months, highlighting the need for increased awareness of this condition post-rhinoplasty.
C-reactive protein (CRP) concentrations rise in response to tissue injury or infection. Circulating pentameric CRP (pCRP) localizes to damaged tissue where it leads to complement activation and further tissue damage. In-depth knowledge of the pCRP activation mechanism is essential to develop therapeutic strategies to minimize tissue injury.
View Article and Find Full Text PDFTissue damage in burn injury leads to a rapid increase of leukocytes and acute phase reactants. Plasma levels of C-reactive protein (CRP) rise within hours after the insult. No deficiency of this protein has been reported in humans, suggesting it plays a pivotal role in innate immunity.
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