Publications by authors named "Benedetta Sargenti"
Background: Incisional hernia is a common short- and long-term complication of laparotomy and can lead to significant morbidity. The aim of this systematic review and meta-analysis is to provide an up-to-date overview of the laparotomy closure method in elective and emergency settings with the prophylactic mesh augmentation technique.
Methods: The Scopus, PubMed, and Web of Science databases were screened without time restrictions up to 21 June 2022 using the keywords 'laparotomy closure', 'mesh', 'mesh positioning', and 'prophylactic mesh', and including medical subject headings terms.
Article Synopsis
- Non-operative management (NOM) for uncomplicated acute appendicitis is a viable alternative to surgery, with this study comparing outpatient (outNOM) and inpatient (inNOM) approaches.
- The study involved 668 patients, showing that outNOM was non-inferior to inNOM in terms of the rate of appendectomies within 30 days and had a shorter average hospital stay (0.89 days vs. 3.94 days).
- Though some outNOM patients visited the emergency department unexpectedly, overall safety and effectiveness of outpatient NOM were supported, indicating a need for further research.
Article Synopsis
- Recent research highlights the growing use of less invasive treatments for acute calculous cholecystitis (ACC) and seeks a reliable method to identify high-risk patients who may benefit from these alternatives.
- The S.P.Ri.M.A.C.C. study observed over 1,200 patients across various centers and assessed different preoperative risk prediction models, including the newly validated Chole-risk score.
- Results indicated that while the Chole-risk score was validated, the POSSUM Physiological Score was found to be the best predictor of complications after early cholecystectomy, demonstrating very high sensitivity for both mortality and major morbidity outcomes.