Publications by authors named "Benedetta Fumagalli"
Article Synopsis
- * Out of 191 adult ARDS patients on VV ECMO, 69% successfully switched to PSV, which led to better respiratory mechanics, increased compliance, and lower pulmonary shunt fraction.
- * The findings suggest that PSV during VV ECMO is not only possible but may improve patient outcomes, with 94% of those transitioned to PSV being weaned from ECMO and a high percentage being discharged alive from ICU.
Article Synopsis
- The study investigates the effects of helmet CPAP on oxygenation levels in hypoxemic patients, analyzing improvements linked to PEEP or oxygen fraction.
- A test called the "ZEEP-PEEP test" was developed to determine whether improvements in oxygenation after helmet application were due to PEEP or better oxygen delivery.
- Results showed significant oxygenation improvements in patients after applying helmet CPAP, with 41% of patients responding positively to PEEP, while the ZEEP-PEEP test could help identify those who would benefit from PEEP use.
Mortality prediction for patients with the severe acute respiratory distress syndrome (ARDS) supported with veno-venous extracorporeal membrane oxygenation (VV-ECMO) is challenging. Clinical variables at baseline and on day 3 after initiation of ECMO support of all patients treated from October 2010 through April 2020 were analyzed. Multivariate logistic regression analysis was used to identify score variables.
View Article and Find Full Text PDFBackground: Arterial lines and central venous catheter (CVC) allow to monitor patients' acid-base status and gas exchange. Their placement and maintenance may however be burdened by severe complications. Midline Catheters (MC) are peripheral venous accesses that are less invasive and easier to insert compared to CVC and arterial lines.
View Article and Find Full Text PDFAn increased risk of deep vein thrombosis (DVT) has been reported in critical COVID-19 patients, despite adequate thromboprophylaxis, and most of DVT are probably asymptomatic. As a screening approach has been advocated, the best examination protocol is unknown. The objective of this study is to assess the role of a Complete Duplex Ultrasound (CDUS) examination in detecting DVT in a large population of COVID-19 patients admitted to intensive care unit (ICU) for respiratory failure.
View Article and Find Full Text PDFVeno-venous extracorporeal membrane oxygenation (V-V ECMO) in acute respiratory distress syndrome (ARDS) improves gas exchange and allows lung rest, thus minimizing ventilation-induced lung injury. In the last forty years, a major technological and clinical improvement allowed to dramatically improve the outcome of patients treated with V-V ECMO. However, many aspects of the care of patients on V-V ECMO remain debated.
View Article and Find Full Text PDFUnlabelled: Patients on extracorporeal support for severe acute respiratory distress syndrome may require a prolonged period of deep sedation. In these patients, volatile sedation may represent a valid alternative to IV drugs. The aim of our study was to describe the feasibility of volatile sedation in a large cohort of acute respiratory distress syndrome patients undergoing venovenous extracorporeal membrane oxygenation and ultraprotective ventilation.
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