Timing of intrathecal baclofen therapy in persons with acquired brain injury: influence on outcome.

Objective: Evaluation of the effects of intrathecal baclofen therapy (ITB) delivered by a pump implanted at a very early stage in acquired brain injury (ABI).

Study Design: This investigation was a longitudinal prospective observational study, including a series of 13 ABI implanted within 6 months of the acute events.

Main Outcome Measure: The Modified Ashworth Scale (MAS) and Spasms Frequency Score (SFS) have been used as a primary outcome measure.