Changes in lymphocyte subpopulations and CD3+/DR+ expression in sepsis.

Objective: To detect lymphocyte subpopulations and CD3+/DR + expression in sepsis.

Methods: In a prospective clinical study we evaluated subpopulations of lymphocytes and percentage of CD3+/HLA-DR+ lymphocytes using two-color flow cytometry in 40 patients with sepsis and compared them with 34 healthy adults.

Results: Septic patients, when compared with healthy controls, have significantly lower percentage and absolute numbers of total T lymphocytes and CD4 T lymphocytes (P < 0.