Change in serum 25-hydroxyvitamin D and parallel change in depressive symptoms in Dutch older adults.

Objectives: Previous prospective studies on the association between vitamin D status and depression used a single 25-hydroxyvitamin D (25(OH)D) measurement. We investigated the association between change in serum 25(OH)D and parallel change in depressive symptoms over time in Dutch older adults.

Design: A population-based, prospective study in two cohorts of older men and women from the Longitudinal Aging Study Amsterdam.