Hemoglobins F, A , and E levels in Laotian children aged 6-23 months with Hb E disorders: Effect of age, sex, and thalassemia types.

Introduction: Determination of hemoglobins (Hbs) F, A and E is crucial for diagnosis of thalassemia. This study determined the levels of Hbs F, A and E in children aged 6-23 months and investigated the effect of age, sex, and types of thalassemia on the expression of these Hbs.

Methods: A total of 698 blood samples of Laotian children including 272 non-Hb E, 271 Hb E heterozygotes, and 155 Hb E homozygotes were collected.