Risk of noncommunicable diseases and associated factors in Algerian adolescents (10-19 years old).

Objective: Noncommunicable diseases (NCDs) are a public health problem and their prevalence is increasing worldwide at an alarming rate. The objective of this study was to assess the predictive factors for NCDs in adolescents.

Material And Methods: The study included adolescents enrolled in public establishments in Constantine (east of Algeria).

Ramadan Fasting and NCDs-Example of the Diabetes.

Although Ramadan lasts only for 1 month each year, it can be accompanied by significant changes in: both energy and nutritional intake; in the diet composition; in the working hours; and the usual way of life. The majority of practitioners consume two meals, one after sunset () and one before dawn (). During this month, it is also an opportunity to share a meal with family and friends, a period of highly intensified socialization.

HLA-E circulating and genetic determinants in schizophrenia and bipolar disorder.

Schizophrenia (SZ) and bipolar disorders (BD) are severe mental illnesses that lack reliable biomarkers to guide diagnosis and management. As immune dysregulation is associated with these disorders, we utilized the immunoregulatory functions of the natural killer cell inhibitory HLA-E locus to investigate the relationships between HLA-E genetic and expression diversities with SZ and BD risk and severity. Four hundred and forty-four patients meeting DSM-IV criteria for SZ (N = 161) or BD (N = 283) were compared to 160 heathy controls (HC).

[Comorbidity schizophrenia and diabetes mellitus in Algeria - A study of risk factors].

Background: The combination of schizophrenia and diabetes mellitus presents a public health problem in the world. Several studies have been carried out for the analysis of this comorbidity, including prognostic factors.

Objective: The objective of our study is to determine the risk factors associated with the comorbidity schizophrenia and diabetes mellitus.

Bis(benzene-1,2-diamine-κ(2)N,N')(sulfato-κO)copper(II) monohydrate.

The title complex, [Cu(SO(4))(C(6)H(8)N(2))(2)]·H(2)O, was obtained under hydro-thermal conditions. The Cu(II) ion is five-coordinated in a distorted square-pyramidal manner by four N atoms from two benzene-1,2-diamine ligands at the base and one O atom from a monodentate sulfate anion at the apex of the coordination polyhedron. N-H⋯O hydrogen bonding between the amino functions and the sulfate groups leads to the formation of layers parallel to (001).

Ammonium tris-(tetra-ethyl-ammonium) hexa-cosa-oxidoocta-molybdate.

The structure of the title compound, NH(4)(C(8)H(20)N)(3)[Mo(8)O(26)], is built up by discrete cations and anions, with two formula units in the asymmetric unit. The β-octa-molybdate anions are linked to the ammonium cations via N-H⋯O hydrogen bonding involving terminal oxide groups and to the tetra-ethyl-ammonium cations via weak C-H⋯O inter-actions.

Theoretical study of Escherichia coli peptide deformylase inhibition by several drugs.

Because peptide deformylase (PDF) is essential for the initiation of translation in eubacteria but not in eukaryotes, it is a potentially interesting target for antibiotics. Computer simulation using docking software can be used to model protein-ligand interactions, and in this brief report we describe its use in optimizing the design in PDF-directed inhibitors. PDF was used as target for a set of five inhibitors with substantial structural differences.