Double-application of platelet-rich plasma on bone healing in rabbits.

Objective: Platelet-rich plasma (PRP) is considered to enhance bone formation especially at early stages of wound healing, depending on the limited and short life-span of platelets and growth factors. The aim of this study was to evaluate efficacy of double-application of PRP (DA-PRP) on bone healing in a rabbit calvarial defect model.

Study Design: Twenty-eight rabbits, each had two surgically prepared calvarial bone defects (10mm diameter), were included in this study and randomly divided into six groups.

Histopathologic study of rat connective tissue responses to maxillofacial silicone elastomers.

The aim of this histopathologic study was to assess and compare the subcutaneous connective tissue reaction to three different maxillofacial silicone elastomers (Cosmesil, Multisil, Episil). The test materials were directly inserted subcutaneously into the dorsal subcutaneous tissue of Wistar albino rats. Histopathological examinations were done at 7, 30, and 90 days after the implantation procedure.

An unusual presentation of ossifying fibromyxoid tumor of the mandible: a case report.

A 13-year-old boy who complained rapid swelling on the left side of mandible is presented. Histopathological examination revealed ossifying fibromyxoid tumor (OFMT). OFMT is a rare soft-tissue neoplasm that occurs usually in the subcutaneous tissue of the extremties.

The treatment of lymphangioma in the buccal mucosa by radiofrequency ablation: a case report.

Lymphangioma is a benign, hamartomatous tumor of the lymphatic system. It is usually found in the head and neck region and is widely regarded as a developmental lesion rather than a true neoplasia. Most lymphangiomas are present at birth (60%), and by the age of 2 years 80% to 90% are present.

Childhood craniofacial Burkitt's lymphoma presenting as maxillary swelling: report of a case and review of literature.

Burkitt's lymphoma (BL) is an undifferentiated malignant lymphoma comprising of uniformly primitive lymphoreticular cells. The tumor was seen originally in patients in Africa. African type BL usually occurs in the jaws of young children.

Effectiveness of scaling and root planing versus modified Widman flap on nitric oxide synthase and arginase activity in patients with chronic periodontitis.

Background: Nitric oxide (NO) is synthesized from the conversion of L-arginine to L-citrulline by NO synthase (NOS). Arginase, which is an arginine-depleting enzyme, can compete with NOS for the common substrate L-arginine and thus inhibit NO production.

Objectives: In the present study, we aimed to examine the correlation between the arginase and NOS activity in patients with chronic periodontitis and to compare the effects of scaling and root planing and modified Widman flap procedures on enzyme activity.

The expression of p53, p16 proteins and prevalence of apoptosis in oral squamous cell carcinoma. Correlation with mode of invasion grading system.

Objective: Inactivation of p53 and p16 tumor suppressor genes, and apoptosis which is crucial in carcinogenesis have commonly been studied in oral squamous cell carcinoma (OSCC). However, their prognostic value has not yet been clearly established.

Methods: This study was conducted in the Department of Oral Pathology, Faculty of Dentistry, Gazi University, Ankara, Turkey during the period 2002 to 2003 on formalin-fixed paraffin embedded tissue specimens of 12 lip and 18 intraoral primary squamous cell carcinoma cases.

Dentin dysplasia type I: report of atypical cases in the permanent and mixed dentitions.

Dentin dysplasia type I is a rare hereditary disturbance of dentin formation characterized clinically by nearly normal appearing crowns and severe hypermobility of teeth. Radiographic analysis shows obliteration of all pulp chambers, short, blunted, and malformed roots, and periapical radiolucencies of noncarious teeth. This paper presents 2 cases demonstrating both classic and atypical features of type I dentin dysplasia in the mixed and permanent dentitions.

A review of paediatric oral biopsies in Turkey.

Objectives: To determine the site and prevalence of oral lesions and the age and gender of a paediatric population in Turkey.

Design: A review of the archives of pathology departments.

Settings: Six pathology departments in Ankara, Turkey.