Publications by authors named "Benard Langat"

Article Synopsis
  • A study was conducted to understand the genetic diversity of Hepatitis B virus (HBV) among blood donors in Kenya, focusing on how emerging viral traits affect treatment outcomes and cancer risk.
  • Researchers collected 194 serum samples from HBsAg-positive donors in various counties and found that HBV genotype A1 was predominant, comprising 88.14% of the samples, with notable genetic diversity.
  • The analysis revealed 90 different haplotypes with specific mutations indicating immune escape, alongside a high haplotype diversity but low nucleotide diversity, suggesting complex viral evolution in the region.
View Article and Find Full Text PDF
Article Synopsis
  • - Hepatitis B is a rising public health concern in Kenya, prompting the need for widespread vaccination, especially for those not included in the national immunization program; completing the three-dose vaccination series is important for achieving high sero-protection rates.
  • - A study conducted in Nairobi recruited 2,644 outpatient attendees, testing their blood for hepatitis B and offering free vaccine doses to those who tested negative, with a focus on understanding vaccination adherence and the prevalence of HBV.
  • - Results showed that 1.82% of participants tested positive for HBV, with 66% receiving at least one vaccine dose and 51.8% completing the full three doses; vaccination acceptance tended to increase with the patient’s age.
View Article and Find Full Text PDF

The human malaria parasite has evolved complex drug evasion mechanisms to all available antimalarials. To date, the combination of amodiaquine-artesunate is among the drug of choice for treatment of uncomplicated malaria. In this combination, a short acting, artesunate is partnered with long acting, amodiaquine for which resistance may emerge rapidly especially in high transmission settings.

View Article and Find Full Text PDF

Unlabelled: A cross-sectional molecular epidemiological study of Entamoeba species was conducted among asymptomatic Kenyan children with (n = 123) and without (n = 111) HIV infection. The prevalence of E. histolytica was low (0.

View Article and Find Full Text PDF