Alterations of intestinal flora and the effects of probiotics in children with recurrent respiratory tract infection.

Background: Recurrent respiratory tract infection (RRTI) is a disease occurred frequently in preschool children.

Methods: A total of 120 RRTI children were randomly divided into active group, remission group, intervention group and control group, meanwhile 30 healthy children were selected as the healthy group. Children in the intervention group were given oral Bifidobaeterium tetravaccine tablets (Live) for 2 months, while the control group received routine treatment.

[Effect of non-methylated CpG-ODN on serum TGF-β and immune regulation in ovalbumin-sensitized young mice].

Objective: To explore the effect of non-methylated cytosine-phosphate-guanine oligodeoxynucleotides (CpG-ODN) on serum transforming growth factor (TGF)-β and immune regulation in ovalbumin (OVA)-sensitized young mice.

Methods: Thirty female BALB/c mice (2-3 weeks old) were randomly divided into control, model, and CpG-ODN intervention groups. A young mouse model of food allergy was established by OVA sensitization.