Imaging blood-brain barrier dysfunction in drug-resistant epilepsy: A multi-center feasibility study.

Objective: Blood-brain barrier dysfunction (BBBD) has been linked to various neurological disorders, including epilepsy. This study aims to utilize dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) to identify and compare brain regions with BBBD in patients with epilepsy (PWE) and healthy individuals.

Methods: We scanned 50 drug-resistant epilepsy (DRE) patients and 58 control participants from four global specialized epilepsy centers using DCE-MRI.

Healthy children's identification and risk perception of medicines in England.

Background: Children's understanding of medicines has an impact on their behavior toward those medicines, and yet there has been a paucity of studies exploring this area.

Objectives: To assess children's ability to identify and to explore their risk perceptions of medicines.

Methods: One hundred eighty-two children aged 4 to 11 years at 2 primary schools in England completed a worksheet containing photos of foods and pharmaceutical products.