Anti-gp210 and anti-Sp100 antibodies in primary biliary cholangitis.

Background And Study Aims: To determine the sensitivity and specificity of anti-gp210 and anti-Sp100 autoantibodies in primary biliary cholangitis (PBC) PATIENTS AND METHODS: Sera of 106 PBC patients with positive anti-mitochondrial antibodies and 58 healthy blood donors were analyzed. A line immunoassay was used to evaluate the reactivity of anti-gp210 and anti-Sp100 antibodies.

Results: The frequency of anti-gp210 and anti-Sp100 autoantibodies was 29.