A Mechanistic Model for Long COVID Dynamics.

Long COVID, a long-lasting disorder following an acute infection of COVID-19, represents a significant public health burden at present. In this paper, we propose a new mechanistic model based on differential equations to investigate the population dynamics of long COVID. By connecting long COVID with acute infection at the population level, our modeling framework emphasizes the interplay between COVID-19 transmission, vaccination, and long COVID dynamics.

Publication bias in trials registered in the Australian New Zealand Clinical Trials Registry: Is it a problem? A cross-sectional study.

Background: Timely publication of clinical trials is critical to ensure the dissemination and implementation of high-quality healthcare evidence. This study investigates the publication rate and time to publication of randomized controlled trials (RCTs) registered in the Australian New Zealand Clinical Trials Registry (ANZCTR).

Materials And Methods: We conducted a cross-sectional study of RCTs registered with the ANZCTR in 2007, 2009, and 2011.

HOW DOES THE LATENCY PERIOD IMPACT THE MODELING OF COVID-19 TRANSMISSION DYNAMICS?

We introduce two mathematical models based on systems of differential equations to investigate the relationship between the latency period and the transmission dynamics of COVID-19. We analyze the equilibrium and stability properties of these models, and perform an asymptotic study in terms of small and large latency periods. We fit the models to the COVID-19 data in the U.