Study Objective: Young infants with bronchiolitis are at risk for apnea. We seek to determine the rate of apnea in young infants with bronchiolitis and evaluate the performance of a predefined set of risk criteria for identifying infants at high risk for the development of apnea.
Methods: We identified a retrospective cohort study of patients treated in the emergency department (ED) of an urban pediatric tertiary care hospital from November 1995 to June 2000.
Background: N-3 and n-6 polyunsaturated fatty acids (PUFAs) have been hypothesized to have opposing influences on neonatal immune responses that might influence the risk of allergy or asthma. However, both n-3 eicosapentaenoic acid (EPA) and n-6 arachidonic acid (AA) are required for normal fetal development.
Objective: We evaluated whether cord blood fatty acid levels were related to neonatal immune responses and whether n-3 and n-6 PUFA responses differed.
Ann Allergy Asthma Immunol
March 2006
Background: Maternal and perinatal environmental exposures, as well as inherited factors, may influence neonatal immune responses.
Objective: To determine relations of maternal and perinatal exposures to antigen-specific cord blood lymphoproliferative responses.
Methods: In 427 newborns from a Boston pregnancy/birth cohort, lymphoproliferative responses in cord blood mononuclear cells to stimulation with cockroach (Bla g 2), house dust mite (Der f 1), ovalbumin, and mitogen phytohemagglutinin were measured as stimulation index (SI).
Objectives: In a prior uncontrolled study, 23% of children with fever and petechiae without bacteremia or sepsis had a prolonged partial thromboplastin time (PTT). We attempted to validate this finding by comparing the PTTs of children with fever and petechiae who were neither septic nor bacteremic with those of children without fever and petechiae.
Methods: Design.