Background: The pancreatic cystic serous neoplasms are divided into two categories: benign serous cystadenoma (SCA) and malignant serous cystadenocarcinoma. Furthermore, based on the macroscopic appearances, SCAs are subdivided into serous microcystic adenomas (SMAs) and serous oligocystic or macrocystic adenomas.
Aim: Report of a new case of SMA in which we emphasize on the diagnostic difficulties encountered against such tumor despite its relatively radiological easiness compared to the other variants.
Aim: A rare case of colonic carcinoma arising in de novo ulcerative colitis after renal transplantation in a 42-year-old woman is reported.
Case: Clinically, the patient presented ulcerative colitis 8 years after renal transplantation, developed colonic cancer with liver metastasis 2 years later and died one month post operatively. Histologically, the removed tumor was composed of two distinctive elements consisting of adenocarcinoma and choriocarcinoma.
Introduction: Basal cell adenoma (BCA) is a rare benign neoplasm characterized by the basaloid appearance of the tumour cells and the lack of myxo-chondroid stromal component present in pleomorphic adenoma.
Aim: We report a case of basal cell adenoma of membranous type, highly suspected of malignancy because of the presence of mediastinal lymph nodes and pulmonary nodules which finally were related to an associated sarcoidosis.
Observation: Our patient was an 80-year-old woman who presented a swelling of the right parotid two years ago.
Background: Solid pseudopapillary tumors of the pancreas are extremely rare and mostly seen in young females. It is often diagnosed incidentally or during investigations of gastrointestinal complaints.
Aim: Report of a pediatric case of this tumor.
Background: Abdominal desmoid tumors arise in young adults between 20 and 40 years. They are characterized by a local recurrence in 20 to 30% of cases.
Aim: review the clinical and pathologic features of this entity, look for the expression of immunohistochemical markers (actine, desmine, CD34, vimentin) and also to estimate the expression of two potential targets therapy; the hormonal receptors and the CD117.
Background: The ovarian tumors' diagnosis is based on biological and radiologic tests but only the histological examination associated to an immunohistochemical study allow best diagnosis.
Aim: The purposes of this study is to examine inhibin and other markers immunoreactivity to ovarian sex cord-stromal tumors and their histological mimics and to discuss its value in the differential diagnosis.
Methods: We report a retrospective study of 31 cases of ovarian sex cord-stromal tumors and review the clinical, pathologic and immunohistochimical features of these tumors.
Background: Most of the sinonasal tumours are of epithelial origin. Leiomyomas are very uncommon in the upper respiratory tract and extremely rare in the nasal cavity and paranasal sinuses. They account for less than 2.
View Article and Find Full Text PDFBackground: Swyer syndrome is a distinct type of pure gonadal dysgenesis characterized by a 46 XY karyotype in female phenotypic patients. It shows an abnormality in testicular differentiation. It is usually revealed by primary amenorrhea.
View Article and Find Full Text PDFBackground: The intraoperative frozen section is a well established procedure for rapid diagnosis that helps in making therapeutic decisions.
Aim: Assessment of the accuracy of frozen section diagnosis and analysis of the causes of its discordance.
Methods: A retrospective review of 1695 surgical specimens performed in 1207 patients between January 2002 and April 2005.
Objective: The purpose of this study was to assess the value of intraoperative frozen section diagnosis in thyroid surgery and determine its limitations.
Methods: This retrospective study examined the results of 409 frozen sections of thyroid specimens analyzed over the 4-year period and their correlations with the final histological examination.
Results: In our series, frozen section diagnosis was concordant with subsequent histopathological examination in 96.
Aims: To study the immunohistochemical expression of HHV8 in Kaposi's lesions and in other vascular lesions and to determine the utility of this technique in differentiating between Kaposi's disease (KD) and other vascular lesions.
Methods: Fixed, paraffin-embedded tissue sections from 25 cases of KD, 9 cases of hemangioma, 2 cases of angiolymphoid hyperplasia with eosinophilia and 9 cases of angiosarcoma were examined immunohistochemically using the monoclonal antibody monoclonal LNA 53 (ABI). Strong, nuclear and granular staining in at least a cell was considered as a positive result.
In a retrospective study of the specimens of gastric polypectomy, carried out between January 1992 and December 2002, we analysed the demographic and histological aspects of 65 polyps. This study revealed hyperplastic polyps in 66%, adenomatous lesions in 9.2%, Peutz-Jeghers polyps in 7.
View Article and Find Full Text PDFCastleman disease or angiofollicular lymph node hyperplasia is a rare disease of unknown cause with polymorphic clinical features that raises many diagnostic and therapeutic problems. The unifocal, localized, pseudoneoplastic form, first described in 1956, has a good prognosis, but the multifocal form has a more aggressive course. Three histological types have been identified: hyaline vascular, plasma cell and mixed.
View Article and Find Full Text PDFSuprasellar germinomas are frequent in childhood and adolescence, particularly in male sex. The clinical and neuroendocrine abnormalities depend of tumor localization: Increased intracranial pressure, visual disturbances, hypopituitarism, Parinaud syndrome. We report two cases of suprasellar germinoma in young male patients (16 and 18 years old).
View Article and Find Full Text PDFMycosis fungoides is an epidermotropic cutaneous T lymphoma. It's a non Hodgkinian lymphoma. We report the results of a retrospective review of 11 mycosis fungoide seen during 22 years.
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