Background: Clostridioides difficile infection (CDI) is a leading cause of healthcare-associated (HA) diarrhoea, contributing to patient morbidity and prolonged length-of-stay (LOS). We retrospectively assessed CDI over a decade in a national neurosurgical centre, with a multi-disciplinary approach to CDI surveillance and antimicrobial stewardship, by comparing CDI patients with other patient groups.
Methods: Data on CDI in neurosurgical inpatients between January 2012 and December 2021 were collated.
Background: Chronic subdural hematoma (cSDH) is a common pathology, and recurrence is a common complication, which may be predicted by certain patient and radiologic factors. Empiric radiologic surveillance has been shown to convey no benefit.
Methods: A retrospective review of a prospectively collated database was performed.
Traumatic brain injury (TBI) is a leading cause of death and disability, especially in young persons, and constitutes a major socioeconomic burden worldwide. It is regarded as the leading cause of mortality and morbidity in previously healthy young persons. Most of the mechanisms underpinning the development of secondary brain injury are consequences of disruption of the complex relationship between the cells and proteins constituting the neurovascular unit or a direct result of loss of integrity of the tight junctions (TJ) in the blood-brain barrier (BBB).
View Article and Find Full Text PDFTuberculosis (TB) remains endemic in many parts of the developing world and is increasingly seen in the developed world due to migration. A total of 1.3 million people die annually from the disease.
View Article and Find Full Text PDFHydatid disease is a parasitic infection linked to the Echinococcus granulosus tapeworm. Infected cysts can present anywhere in the human body, but the liver is the most frequently involved organ, followed by the lungs. The prognosis is generally poor and may be comparable to that of neoplastic disease.
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