Publications by authors named "Ben Goldstein"
Objective: To examine early sedation patterns, as well as the association of dexmedetomidine exposure, with clinical and functional outcomes among mechanically ventilated patients with moderate-severe traumatic brain injury (msTBI).
Design: Retrospective cohort study with prospectively collected data.
Setting: Eighteen Level-1 Trauma Centers, United States.
Article Synopsis
- The study aimed to analyze how beta-blockers are used in critically ill patients after experiencing moderate to severe traumatic brain injury (TBI) and to assess their impact on recovery outcomes.
- Conducted in 18 U.S. trauma center ICUs, it included patients 17 years and older with significant TBI, evaluating factors like length of hospital stay and mortality rates along with the primary outcome of functional recovery at 6 months.
- Results showed that only 13% of eligible patients received early beta-blocker treatment, with no significant difference in recovery outcomes or associated benefits based on beta-blocker use.
Background: Early hypotension after severe traumatic brain injury (sTBI) is associated with increased mortality and poor long-term outcomes. Current guidelines suggest the use of intravenous vasopressors, commonly norepinephrine and phenylephrine, to support blood pressure after TBI. However, guidelines do not specify vasopressor type, resulting in variation in clinical practice.
View Article and Find Full Text PDFIntroduction: We analyzed trends and explored implications of no-show rates in adult urology from provider related characteristics at an academic program.
Methods: No-show rates were determined from electronic health records of appointments in adult urology at Duke University Medical Center and affiliated clinics between January 2014 and December 2016. t-Test, Wilcoxon rank sum and ANOVA were employed.
Background: Sleep disturbances are a prominent feature of bipolar disorder (BP). However, it remains unclear how sleep phenotypes may evolve among at-risk youth, and their relevance to BP onset.
Methods: Pittsburgh Bipolar Offspring Study (BIOS) offspring (ages 10-18) and their parents completed assessments approximately every two years pertaining to current psychopathology and offspring sleep habits.
Study Objective: The 2010 provision of the Patient Protection and Affordable Care Act (ACA) extended eligibility for health insurance for young adults aged 19 to 25 years. It is unclear, however, how expanded coverage changes health care behavior and promotes efficient use of emergency department (ED) services. Our objective was to use population-level emergency department data to characterize any changes in diagnoses seen in ED among young adults since the implementation of the ACA dependent coverage expansion.
View Article and Find Full Text PDFObjectives: Previous studies have suggested that the sum of Attention, Aggression, and Anxious/Depressed subscales of Child Behavior Checklist (CBCL-PBD; pediatric bipolar disorder phenotype) may be specific to pediatric bipolar disorder (BP). The purpose of this study was to evaluate the usefulness of the CBCL and CBCL-PBD to identify BP in children <12 years old.
Methods: A sample of children with BP I, II, and not otherwise specified (NOS) (n = 157) ascertained through the Course and Outcome for Bipolar Disorder in Youth (COBY) study were compared with a group of children with major depressive/anxiety disorders (MDD/ANX; n = 101), disruptive behavior disorder (DBD) (n = 127), and healthy control (HC) (n = 128).