When biotech crosses borders.

Rapid action is needed to address loopholes in the international governance of self-dispersing genetically modified organisms (GMOs) purposefully released for the management of wild species and diseases.

Mind the sustainability gap.

Despite increasing efforts to reach sustainability, key global biophysical indicators such as climate change and biodiversity loss continue to deteriorate rather than improve. Ongoing failure to move towards sustainability calls into question the focus of current research and policy. We recommend two strategies for progress.