Publications by authors named "Ben E Abbotts"
Article Synopsis
- Chemokines influence the movement of blood cells, which is crucial in various immune diseases, notably in acute and chronic graft-versus-host disease (GVHD).
- In chronic GVHD of the skin, levels of CXCR3-binding chemokines (CXCL9, CXCL10, and CXCL11) were significantly higher in patients, while there was a notable drop in certain T cells (CD4(+) expressing CXCR3) in their blood.
- The increase in CXCL10 seen in acute GVHD evolves in chronic cases, leading to the recruitment of CD4(+) T cells instead, highlighting the important role of specific chemokines in this disease's pathology.
